Introduction：Basic information about CAS 153322-05-5|Lanicemine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Lanicemine |
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| CAS Number | 153322-05-5 | Molecular Weight | 198.264 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 307.7±27.0 °C at 760 mmHg |
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| Molecular Formula | C13H14N2 | Melting Point | / |
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| MSDS | / | Flash Point | 160.6±10.8 °C |
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Names
| Name | lanicemine |
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| Synonym | More Synonyms |
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Lanicemine BiologicalActivity
| Description | Lanicemine (AZD6765) is a low-trapping NMDA channel blocker with a binding (Ki) of 0.56-2.1 μM[1]. |
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| Related Catalog | Signaling Pathways >>Neuronal Signaling >>iGluRResearch Areas >>Neurological DiseaseSignaling Pathways >>Membrane Transporter/Ion Channel >>iGluR |
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| Target | NMDA Channel Blocker[1] |
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| References | [1]. Sanacora G, et al. Lanicemine: a low-trapping NMDA channel blocker produces sustained antidepressant efficacywith minimal psychotomimetic adverse effects. Mol Psychiatry. 2014 Sep;19(9):978-85. |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 307.7±27.0 °C at 760 mmHg |
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| Molecular Formula | C13H14N2 |
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| Molecular Weight | 198.264 |
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| Flash Point | 160.6±10.8 °C |
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| Exact Mass | 198.115692 |
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| LogP | 1.63 |
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| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
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| Index of Refraction | 1.602 |
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| InChIKey | FWUQWDCOOWEXRY-ZDUSSCGKSA-N |
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| SMILES | NC(Cc1ccccn1)c1ccccc1 |
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Synonyms
| UNII:9TMU325RK3 |
| (S)-(+)-1-phenyl-2-(pyridin-2-yl)ethylamine |
| 2-Pyridineethanamine, α-phenyl-, (αS)- |
| (1S)-1-Phenyl-2-(2-pyridinyl)ethanamine |
| 9TMU325RK3 |
| lanicemine |
| MFCD00924222 |
