Introduction：Basic information about CAS 109304-04-3|2-Aminopurine-9-beta-D-(2'-deoxy-2'-fluoro)arabino-riboside, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-Aminopurine-9-beta-D-(2'-deoxy-2'-fluoro)arabino-riboside |
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| CAS Number | 109304-04-3 | Molecular Weight | 269.23 |
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| Density | 2.0±0.1 g/cm3 | Boiling Point | 662.9±65.0 °C at 760 mmHg |
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| Molecular Formula | C10H12FN5O3 | Melting Point | / |
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| MSDS | / | Flash Point | 354.7±34.3 °C |
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Names
| Name | 2-AMinopurine -9-beta-D-(2'-deoxy-2'-fluoro)arabino-riboside |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | 2-Amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/AnalogResearch Areas >>Others |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 2.0±0.1 g/cm3 |
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| Boiling Point | 662.9±65.0 °C at 760 mmHg |
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| Molecular Formula | C10H12FN5O3 |
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| Molecular Weight | 269.23 |
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| Flash Point | 354.7±34.3 °C |
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| Exact Mass | 269.092407 |
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| LogP | -0.70 |
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| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
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| Index of Refraction | 1.834 |
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| InChIKey | REZWVJHKIBWHOX-JVZYCSMKSA-N |
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| SMILES | Nc1ncc2ncn(C3OC(CO)C(O)C3F)c2n1 |
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Synonyms
| 9-(2-Deoxy-2-fluoro-β-L-arabinofuranosyl)-9H-purin-2-amine |
| 9H-Purin-2-amine, 9-(2-deoxy-2-fluoro-β-L-arabinofuranosyl)- |
