Introduction：Basic information about CAS 1415800-38-2|Bromo-PEG5-Boc, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Bromo-PEG5-Boc |
|---|
| CAS Number | 1415800-38-2 | Molecular Weight | 429.344 |
|---|
| Density | 1.2±0.1 g/cm3 | Boiling Point | 453.9±40.0 °C at 760 mmHg |
|---|
| Molecular Formula | C17H33BrO7 | Melting Point | / |
|---|
| MSDS | / | Flash Point | 228.3±27.3 °C |
|---|
Names
| Name | Bromo-PEG5-t-butyl ester |
|---|
| Synonym | More Synonyms |
|---|
Bromo-PEG5-Boc BiologicalActivity
| Description | Bromo-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
|---|
| Target | PEGs Alkyl/ether |
|---|
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
|---|
| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
|---|
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|
| Boiling Point | 453.9±40.0 °C at 760 mmHg |
|---|
| Molecular Formula | C17H33BrO7 |
|---|
| Molecular Weight | 429.344 |
|---|
| Flash Point | 228.3±27.3 °C |
|---|
| Exact Mass | 428.140961 |
|---|
| LogP | 0.96 |
|---|
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
|---|
| Index of Refraction | 1.466 |
|---|
| InChIKey | CFAPOEDUPYZKFH-UHFFFAOYSA-N |
|---|
| SMILES | CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCBr |
|---|
Synonyms
| MFCD22683304 |
| 2-Methyl-2-propanyl 1-bromo-3,6,9,12,15-pentaoxaoctadecan-18-oate |
| 3,6,9,12,15-Pentaoxaoctadecan-18-oic acid, 1-bromo-, 1,1-dimethylethyl ester |
