Introduction：Basic information about CAS 1415800-41-7|Azide-PEG5-Boc, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Azide-PEG5-Boc |
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| CAS Number | 1415800-41-7 | Molecular Weight | 391.460 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C17H33N3O7 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Azide-PEG5-t-butyl ester |
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| Synonym | More Synonyms |
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Azide-PEG5-Boc BiologicalActivity
| Description | Azide-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Molecular Formula | C17H33N3O7 |
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| Molecular Weight | 391.460 |
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| Exact Mass | 391.231842 |
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| LogP | 0.27 |
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| InChIKey | RGXALMUKZGZJKF-UHFFFAOYSA-N |
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| SMILES | CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCN=[N+]=[N-] |
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Synonyms
| 2-Methyl-2-propanyl 1-azido-3,6,9,12,15-pentaoxaoctadecan-18-oate |
| 3,6,9,12,15-Pentaoxaoctadecan-18-oic acid, 1-azido-, 1,1-dimethylethyl ester |
| MFCD22683303 |
