Introduction：Basic information about CAS 174569-25-6|m-PEGn-NHS ester, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | m-PEGn-NHS ester |
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| CAS Number | 174569-25-6 | Molecular Weight | 1787.0688 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | (C2H4O)nC8H11NO5 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Methoxy-PEG-propionicacid-N-succinimidylester |
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m-PEGn-NHS ester BiologicalActivity
| Description | m-PEGn-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. |
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Chemical & Physical Properties
| Molecular Formula | (C2H4O)nC8H11NO5 |
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| Molecular Weight | 1787.0688 |
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