CAS 2055014-96-3|Propargyl-PEG8-Boc

Introduction:Basic information about CAS 2055014-96-3|Propargyl-PEG8-Boc, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NamePropargyl-PEG8-Boc
CAS Number2055014-96-3Molecular Weight492.600
Density1.1±0.1 g/cm3Boiling Point528.4±45.0 °C at 760 mmHg
Molecular FormulaC24H44O10Melting Point/
MSDS/Flash Point220.3±28.8 °C

Names

NamePropargyl-PEG8-t-butyl ester
SynonymMore Synonyms

Propargyl-PEG8-Boc BiologicalActivity

DescriptionPropargyl-PEG7-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Noah Bell, et al. Compounds and methods for inhibiting phosphate transport. WO2012054110A2.

Chemical & Physical Properties

Density1.1±0.1 g/cm3
Boiling Point528.4±45.0 °C at 760 mmHg
Molecular FormulaC24H44O10
Molecular Weight492.600
Flash Point220.3±28.8 °C
Exact Mass492.293457
LogP-0.54
Vapour Pressure0.0±1.4 mmHg at 25°C
Index of Refraction1.460
InChIKeyIGEMRRCREJIMCQ-UHFFFAOYSA-N
SMILESC#CCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)OC(C)(C)C
Storage condition2-8°C

Synonyms

2-Methyl-2-propanyl 4,7,10,13,16,19,22,25-octaoxaoctacos-27-yn-1-oate
MFCD28976700
4,7,10,13,16,19,22,25-Octaoxaoctacos-27-yn-1-oic acid, 1,1-dimethylethyl ester
CAS 205368-54-3|N-Methylguanosine cyclic 3',5'-(hydrogen phosphate)
CAS 2055022-18-7|Propargyl-PEG10-acid
Recommended......
TOP