Introduction：Basic information about CAS 2055022-18-7|Propargyl-PEG10-acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Propargyl-PEG10-acid |
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| CAS Number | 2055022-18-7 | Molecular Weight | 524.599 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 593.9±50.0 °C at 760 mmHg |
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| Molecular Formula | C24H44O12 | Melting Point | / |
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| MSDS | / | Flash Point | 184.2±23.6 °C |
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Names
| Name | Propargyl-PEG10-acid |
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| Synonym | More Synonyms |
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Propargyl-PEG10-acid BiologicalActivity
| Description | Propargyl-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 593.9±50.0 °C at 760 mmHg |
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| Molecular Formula | C24H44O12 |
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| Molecular Weight | 524.599 |
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| Flash Point | 184.2±23.6 °C |
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| Exact Mass | 524.283264 |
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| LogP | -2.95 |
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| Vapour Pressure | 0.0±3.6 mmHg at 25°C |
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| Index of Refraction | 1.469 |
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Synonyms
| 4,7,10,13,16,19,22,25,28,31-Decaoxatetratriacont-33-yn-1-oic acid |
| MFCD28976690 |
