CAS 2055042-66-3|Hydroxy-PEG9-Boc

Introduction:Basic information about CAS 2055042-66-3|Hydroxy-PEG9-Boc, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameHydroxy-PEG9-Boc
CAS Number2055042-66-3Molecular Weight542.66
Density/Boiling Point/
Molecular FormulaC25H50O12Melting Point/
MSDS/Flash Point/

Names

NameHydroxy-PEG9-t-butyl ester
SynonymMore Synonyms

Hydroxy-PEG9-Boc BiologicalActivity

DescriptionHydroxy-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

Alkyl/ether

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

Molecular FormulaC25H50O12
Molecular Weight542.66

Synonyms

MFCD30182029
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