CAS 2055022-35-8|Propargyl-PEG9-OH

Introduction:Basic information about CAS 2055022-35-8|Propargyl-PEG9-OH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NamePropargyl-PEG9-OH
CAS Number2055022-35-8Molecular Weight452.536
Density1.1±0.1 g/cm3Boiling Point518.0±45.0 °C at 760 mmHg
Molecular FormulaC21H40O10Melting Point/
MSDS/Flash Point267.1±28.7 °C

Names

NamePropargyl-PEG10-alcohol
SynonymMore Synonyms

Propargyl-PEG9-OH BiologicalActivity

DescriptionPropargyl-PEG9-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Satwik Kamtekar, et al. Modified biotin-binding proteins for immobilization. WO2019126734A1.

Chemical & Physical Properties

Density1.1±0.1 g/cm3
Boiling Point518.0±45.0 °C at 760 mmHg
Molecular FormulaC21H40O10
Molecular Weight452.536
Flash Point267.1±28.7 °C
Exact Mass452.262146
LogP-3.11
Vapour Pressure0.0±3.1 mmHg at 25°C
Index of Refraction1.465

Synonyms

MFCD28976698
3,6,9,12,15,18,21,24,27-Nonaoxatriacont-29-yn-1-ol
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