Introduction：Basic information about CAS 329187-86-2|2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite |
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| CAS Number | 329187-86-2 | Molecular Weight | 875.94 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C47H51FN7O7P | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 2'-Fluoro-2'-deoxy-ara-A-3'-phosphoramidite |
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BiologicalActivity
| Description | 2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. |
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Chemical & Physical Properties
| Molecular Formula | C47H51FN7O7P |
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| Molecular Weight | 875.94 |
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| InChIKey | VCCMVPDSLHFCBB-UHFFFAOYSA-N |
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| SMILES | COc1ccc(C(OCC2OC(n3cnc4c(NC(=O)c5ccccc5)ncnc43)C(F)C2OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1 |
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| Storage condition | 2-8℃ |
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