Introduction：Basic information about CAS 501081-76-1|Rilonacept, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Rilonacept |
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| CAS Number | 501081-76-1 | Molecular Weight | / |
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Names
Rilonacept BiologicalActivity
| Description | Rilonacept (Arcalyst), a dimeric fusion protein, is a interleukin 1 inhibitor. Rilonacept consists of the ligand-binding domains of the extracellular portions of the IL-1R components linked to the Fc portion of human IgG1. Rilonacept can be used for the research of cryopyrin-associated periodic syndromes[1]. |
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| Related Catalog | Signaling Pathways >>Immunology/Inflammation >>Interleukin RelatedResearch Areas >>Inflammation/Immunology |
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| Target | IL-1 |
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| In Vitro | Rilonacept 通过充当结合 IL-1β 并阻止其与细胞表面受体相互作用的可溶性诱饵受体来阻断 IL-1α 信号传导，从而减少炎症过程[1]。 |
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| References | [1]. Kapur S, et, al. Rilonacept (arcalyst), an interleukin-1 trap for the treatment of cryopyrin-associated periodic syndromes. P T. 2009 Mar;34(3):138-41. |
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Chemical & Physical Properties
| No Any Chemical & Physical Properties |
