CAS 622379-93-5|2’-β-C-Methyl-3-deazauri dine

Introduction:Basic information about CAS 622379-93-5|2’-β-C-Methyl-3-deazauri dine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name2’-β-C-Methyl-3-deazauri dine
CAS Number622379-93-5Molecular Weight257.24
Density1.6±0.1 g/cm3Boiling Point544.6±50.0 °C at 760 mmHg
Molecular FormulaC11H15NO6Melting Point/
MSDS/Flash Point283.2±30.1 °C

Names

Name4-Hydroxy-1-(2-C-Methyl--D-ribofuranosyl)- 2(1H)-pyridinone
SynonymMore Synonyms

2’-β-C-Methyl-3-deazauri dine BiologicalActivity

Description2’-β-C-Methyl-3-deazauri dine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related CatalogSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/AnalogResearch Areas >>Others
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

Density1.6±0.1 g/cm3
Boiling Point544.6±50.0 °C at 760 mmHg
Molecular FormulaC11H15NO6
Molecular Weight257.24
Flash Point283.2±30.1 °C
Exact Mass257.089935
LogP-0.47
Vapour Pressure0.0±3.3 mmHg at 25°C
Index of Refraction1.669
InChIKeyWAHZSHBKEKNCHG-QCNRFFRDSA-N
SMILESCC1(O)C(O)C(CO)OC1n1ccc(O)cc1=O

Synonyms

2(1H)-Pyridinone, 4-hydroxy-1-(2-C-methyl-β-D-ribofuranosyl)-
4-Hydroxy-1-(2-C-methyl-β-D-ribofuranosyl)-2(1H)-pyridinone
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