Introduction：Basic information about CAS 72713-23-6|Bromo-PEG6-bromide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Bromo-PEG6-bromide |
|---|
| CAS Number | 72713-23-6 | Molecular Weight | 452.18 |
|---|
| Density | / | Boiling Point | / |
|---|
| Molecular Formula | C14H28Br2O6 | Melting Point | / |
|---|
| MSDS | / | Flash Point | / |
|---|
Names
| Name | Br-PEG6-bromide |
|---|
| Synonym | More Synonyms |
|---|
Bromo-PEG6-bromide BiologicalActivity
| Description | Bromo-PEG6-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. |
|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
|---|
| Target | PEGs |
|---|
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
|---|
| References | [1]. Mulyana Y, et al. Oligonuclear polypyridylruthenium(II) complexes incorporating flexible polar and non-polar bridges: synthesis, DNA-binding and cytotoxicity. Dalton Trans. 2011 Feb 21;40(7):1510-23. [2]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |
|---|
Chemical & Physical Properties
| Molecular Formula | C14H28Br2O6 |
|---|
| Molecular Weight | 452.18 |
|---|
| InChIKey | ODSLOCVIDIOUPB-UHFFFAOYSA-N |
|---|
| SMILES | BrCCOCCOCCOCCOCCOCCOCCBr |
|---|
Synonyms
