Introduction：Basic information about CAS 874208-84-1|m-PEG4-CH2-acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | m-PEG4-CH2-acid |
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| CAS Number | 874208-84-1 | Molecular Weight | 250.29 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C11H22O6 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
m-PEG4-CH2-acid BiologicalActivity
| Description | m-PEG4-CH2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. Zuluaga MF, et al. Enhanced prostate cancer targeting by modified protease sensitive photosensitizer prodrugs. Mol Pharm. 2012 Jun 4;9(6):1570-9. |
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Chemical & Physical Properties
| Molecular Formula | C11H22O6 |
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| Molecular Weight | 250.29 |
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| Storage condition | 2-8°C |
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