CAS 874208-93-2|m-PEG5-Boc

Introduction:Basic information about CAS 874208-93-2|m-PEG5-Boc, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Namem-PEG5-Boc
CAS Number874208-93-2Molecular Weight336.421
Density1.0±0.1 g/cm3Boiling Point390.8±32.0 °C at 760 mmHg
Molecular FormulaC16H32O7Melting Point/
MSDS/Flash Point166.2±25.2 °C

Names

NamemPEG5-t-buyl ester
SynonymMore Synonyms

m-PEG5-Boc BiologicalActivity

Descriptionm-PEG5-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Balasingam Radhakrishnan, et al. Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof. US20060018874A1.

Chemical & Physical Properties

Density1.0±0.1 g/cm3
Boiling Point390.8±32.0 °C at 760 mmHg
Molecular FormulaC16H32O7
Molecular Weight336.421
Flash Point166.2±25.2 °C
Exact Mass336.214813
LogP-0.02
Vapour Pressure0.0±0.9 mmHg at 25°C
Index of Refraction1.441
InChIKeyABOAGRJWHPYZKV-UHFFFAOYSA-N
SMILESCOCCOCCOCCOCCOCCC(=O)OC(C)(C)C

Synonyms

MFCD28976703
2,5,8,11,14-Pentaoxaheptadecan-17-oic acid, 1,1-dimethylethyl ester
2-Methyl-2-propanyl 2,5,8,11,14-pentaoxaheptadecan-17-oate
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