Introduction：Basic information about CAS 939028-75-8|pNP-ADPr, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | pNP-ADPr |
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| CAS Number | 939028-75-8 | Molecular Weight | / |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C21H26N6O16P2 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Adenosine 5'-(trihydrogen diphosphate), P'-5-ester with 4-nitrophenyl beta-D-ribofuranoside |
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pNP-ADPr BiologicalActivity
| Description | pNP-ADPr is a colorimetric substrate that used for the first continuous Poly(ADP-ribose) glycohydrolase (PARG) and ADP-ribosyl hydrolase 3 (ARH3) activity assays. pNP-ADPr can be used for the research of poly(ADP-ribose)polymerase (PARP) enzymes[1][2]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| In Vitro | pNP-ADPr is a colorimetric substrate that used for the first continuous Poly(ADP-ribose) glycohydrolase (PARG) and ADP-ribosyl hydrolase 3 (ARH3) activity assays[1]. |
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| References | [1]. Drown BS, et al. Monitoring Poly(ADP-ribosyl)glycohydrolase Activity with a Continuous Fluorescent Substrate. Cell Chem Biol. 2018;25(12):1562-1570.e19. [2]. Nottbohm AC, et al. A colorimetric substrate for poly(ADP-ribose) polymerase-1, VPARP, and tankyrase-1. Angew Chem Int Ed Engl. 2007;46(12):2066-2069. |
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Chemical & Physical Properties
| Molecular Formula | C21H26N6O16P2 |
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| InChIKey | RCULIYXBWRLLMU-GFIYZJRMSA-N |
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| SMILES | Nc1ncnc2c1ncn2C1OC(COP(=O)(OC(C(=O)Oc2ccc([N+](=O)[O-])cc2)C(O)C(O)CO)OP(=O)(O)O)C(O)C1O |
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