CAS 1006592-45-5|Biotin-PEG4-amide-Alkyne

Introduction：Basic information about CAS 1006592-45-5|Biotin-PEG4-amide-Alkyne, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameBiotin-PEG4-amide-Alkyne
CAS Number1006592-45-5Molecular Weight528.662
Density1.174Boiling Point/
Molecular FormulaC24H40N4O7SMelting Point/
MSDS/Flash Point/

Names

Name(3aS,4S,6aR)-Hexahydro-2-oxo-N-(15-oxo-3,6,9,12-tetraoxa-16-azanonadec-18-yn-1-yl)-1H-thieno[3,4-d]imidazole-4-pentanamide

Biotin-PEG4-amide-Alkyne BiologicalActivity

DescriptionBiotin-PEG4-amide-Alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

Density1.174
Molecular FormulaC24H40N4O7S
Molecular Weight528.662
CAS 1006319-98-7|2-METHYL-3-(3-METHYL-PYRAZOL-1-YL)-PROPYLAMINE
CAS 1006614-50-1|trans-2-(3,4-difluorophenyl)cyclopropane-1-carboxylic acid
Recommended......
CAS 109715-12-0|5-(p-Toluenesu CAS 103626-36-4|9H-Purin-6-ami CAS 1028-40-6|4(1H)-Quinazolin CAS 102185-28-4|4-AMINOPHENYLP CAS 1000340-33-9|3,4-Dibromo-1 CAS 10390-14-4|2β-Hydroxy CAS 104-43-8|4-n-Dodecylphenol CAS 104-40-5|4-Nonylphenol CAS 1035-51-4|3-(4-ETHOXYPHENY CAS 10517-44-9|1,3-Propanediam CAS 10534-86-8|Hexaamminecobal CAS 101646-01-9|3,4-DIFLUORO-5 CAS 1011407-68-3|(R)-3-CHLORO- CAS 1092682-87-5|4-Chloro-3-me CAS 1036260-25-9|3-Aminocyclob CAS 105394-83-0|Decarboxy Cipr CAS 106868-09-1|2,2-DI-N-OCTYL CAS 1005615-47-3|3-(4-BROMO-PY CAS 104775-66-8|2-amino-4-chlo CAS 10569-35-4|2-phenyl-3-(2-t
Disclaimer

This site is a non-commercial website, not accept any sponsorship and advertising. The content is collated from the Internet, does not represent the position of this site, for personal reference only, please distinguish by yourself! The belongs to the original author.

Copyright © 2025 All Rights Reserved.

TOP