Introduction：Basic information about CAS 102067-84-5|Sappanone A, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Sappanone A |
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| CAS Number | 102067-84-5 | Molecular Weight | 284.263 |
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| Density | 1.5±0.1 g/cm3 | Boiling Point | 605.5±55.0 °C at 760 mmHg |
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| Molecular Formula | C16H12O5 | Melting Point | / |
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| MSDS | / | Flash Point | 233.2±25.0 °C |
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Names
| Name | Sappanone A |
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| Synonym | More Synonyms |
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Sappanone A BiologicalActivity
| Description | Sappanone A is a homoisoflavanone which exhibits anti-inflammatory effects via modulation of Nrf2 and NF-κB. Sappanone can attenuate allergic airway inflammation in Ovalbumin-induced asthma[1]. |
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| Related Catalog | Signaling Pathways >>NF-κB >>Keap1-Nrf2Research Areas >>Inflammation/Immunology |
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| References | [1]. Lee S, et, al. Sappanone A exhibits anti-inflammatory effects via modulation of Nrf2 and NF-κB. Int Immunopharmacol. 2015 Sep;28(1):328-36. [2]. Liu X, et, al. Sappanone A Attenuates Allergic Airway Inflammation in Ovalbumin-Induced Asthma. Int Arch Allergy Immunol. 2016;170(3):180-6. |
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Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
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| Boiling Point | 605.5±55.0 °C at 760 mmHg |
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| Molecular Formula | C16H12O5 |
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| Molecular Weight | 284.263 |
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| Flash Point | 233.2±25.0 °C |
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| Exact Mass | 284.068481 |
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| LogP | 2.49 |
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| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
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| Index of Refraction | 1.754 |
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| InChIKey | KVYZXXBTJHJISR-YHYXMXQVSA-N |
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| SMILES | O=C1C(=Cc2ccc(O)c(O)c2)COc2cc(O)ccc21 |
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Synonyms
| 3-(3,4-Dihydroxybenzylidene)-7-hydroxy-2,3-dihydro-4H-chromen-4-one |
| 4H-1-Benzopyran-4-one, 3-[(3,4-dihydroxyphenyl)methylene]-2,3-dihydro-7-hydroxy- |
