Introduction：Basic information about CAS 1028089-05-5|Tos-PEG7-OH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Tos-PEG7-OH |
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| CAS Number | 1028089-05-5 | Molecular Weight | 480.569 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 554.5±50.0 °C at 760 mmHg |
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| Molecular Formula | C21H36O10S | Melting Point | / |
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| MSDS | / | Flash Point | 289.1±30.1 °C |
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Names
| Name | PEG8-Tos |
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| Synonym | More Synonyms |
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Tos-PEG7-OH BiologicalActivity
| Description | Tos-PEG7-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 554.5±50.0 °C at 760 mmHg |
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| Molecular Formula | C21H36O10S |
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| Molecular Weight | 480.569 |
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| Flash Point | 289.1±30.1 °C |
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| Exact Mass | 480.202911 |
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| LogP | -1.30 |
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| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
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| Index of Refraction | 1.488 |
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| InChIKey | OPGOVMSKPDWRRQ-UHFFFAOYSA-N |
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| SMILES | Cc1ccc(S(=O)(=O)OCCOCCOCCOCCOCCOCCOCCO)cc1 |
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Synonyms
| MFCD24539472 |
| 2,5,8,11,14,17,20-Heptaoxadocosan-22-ol, benzenesulfonate |
| 2,5,8,11,14,17,20-Heptaoxadocosan-22-yl benzenesulfonate |
