Introduction：Basic information about CAS 1036207-61-0|Tetrapeptide-30, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Tetrapeptide-30 |
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| CAS Number | 1036207-61-0 | Molecular Weight | 500.596 |
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| Density | 1.256±0.06 g/cm3(Predicted) | Boiling Point | 931.5±65.0 °C(Predicted) |
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| Molecular Formula | C22H40N6O7 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
Tetrapeptide-30 BiologicalActivity
| Description | Tetrapeptide-30 is a skin-brightening peptide consisting of four amino acids. Tetrapeptide-30 can act as a tyrosinase inhibitor, lightening hyperpigmentation and evening out skin tone by reducing the amount of tyrosinase and inhibiting melanocyte activation[1]. |
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| Related Catalog | Research Areas >>Inflammation/ImmunologySignaling Pathways >>Metabolic Enzyme/Protease >>Tyrosinase |
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| In Vitro | Tetrapeptide-30 (0-10 μg/mL, 24 h) can effectively reduce UVB-induced gene expression of IL-6, TNF-α and POMC (proopiomelanocorticotropin), and also decreased IL-8 gene expression in a dose-dependent manner[1]. Tetrapeptide-30 (PKEK) is highly hydrophilic and has good skin penetration in microemulsion[2]. |
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| References | [1]. Alessandra Marini, et al. Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects. Exp Dermatol. 2012 Feb;21(2):140-6. [2]. Reinhard H H Neubert, et al. Dermal peptide delivery using enhancer moleculs and colloidal carrier systems. Part II: Tetrapeptide PKEK. Eur J Pharm Biopharm. 2018 Mar;124:28-33. |
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Chemical & Physical Properties
| Density | 1.256±0.06 g/cm3(Predicted) |
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| Boiling Point | 931.5±65.0 °C(Predicted) |
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| Molecular Formula | C22H40N6O7 |
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| Molecular Weight | 500.596 |
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| InChIKey | LYHZXMVNRVAAJA-QAETUUGQSA-N |
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| SMILES | NCCCCC(NC(=O)C(CCC(=O)O)NC(=O)C(CCCCN)NC(=O)C1CCCN1)C(=O)O |
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