Introduction：Basic information about CAS 109304-16-7|Purine-9-beta-D-(2'-deoxy-2'-fluoro) arabinoriboside, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Purine-9-beta-D-(2'-deoxy-2'-fluoro) arabinoriboside |
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| CAS Number | 109304-16-7 | Molecular Weight | 254.22 |
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| Density | 1.9±0.1 g/cm3 | Boiling Point | 544.8±60.0 °C at 760 mmHg |
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| Molecular Formula | C10H11FN4O3 | Melting Point | / |
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| MSDS | / | Flash Point | 283.3±32.9 °C |
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Names
| Name | Purine -9-beta-D-(2'-deoxy-2'-fluoro) arabinoriboside |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | 9-(2’-Deoxy-2’-fluoro-β-D-arabinofuranosyl)-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/AnalogResearch Areas >>Others |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 1.9±0.1 g/cm3 |
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| Boiling Point | 544.8±60.0 °C at 760 mmHg |
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| Molecular Formula | C10H11FN4O3 |
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| Molecular Weight | 254.22 |
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| Flash Point | 283.3±32.9 °C |
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| Exact Mass | 254.081512 |
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| LogP | -0.67 |
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| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
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| Index of Refraction | 1.772 |
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| InChIKey | HLBLWLNFMONEHG-IBCQBUCCSA-N |
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| SMILES | OCC1OC(n2cnc3cncnc32)C(F)C1O |
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Synonyms
| MFCD25542492 |
| 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine |
| 9H-Purine, 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)- |
