Introduction：Basic information about CAS 1421933-33-6|S-Acetyl-PEG3-C2-acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | S-Acetyl-PEG3-C2-acid |
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| CAS Number | 1421933-33-6 | Molecular Weight | 280.338 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 421.4±40.0 °C at 760 mmHg |
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| Molecular Formula | C11H20O6S | Melting Point | / |
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| MSDS | / | Flash Point | 208.7±27.3 °C |
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Names
| Name | S-acetyl-PEG3-acid |
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| Synonym | More Synonyms |
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S-Acetyl-PEG3-C2-acid BiologicalActivity
| Description | S-Acetyl-PEG3-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 421.4±40.0 °C at 760 mmHg |
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| Molecular Formula | C11H20O6S |
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| Molecular Weight | 280.338 |
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| Flash Point | 208.7±27.3 °C |
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| Exact Mass | 280.098053 |
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| LogP | -0.17 |
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| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
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| Index of Refraction | 1.489 |
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Synonyms
| 6,9,12-Trioxa-3-thiapentadecan-15-oic acid, 2-oxo- |
| 2-Oxo-6,9,12-trioxa-3-thiapentadecan-15-oic acid |
| MFCD22574765 |
