Introduction：Basic information about CAS 1422023-54-8|Propargyl-PEG7-alcohol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Propargyl-PEG7-alcohol |
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| CAS Number | 1422023-54-8 | Molecular Weight | 364.431 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 447.2±40.0 °C at 760 mmHg |
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| Molecular Formula | C17H32O8 | Melting Point | / |
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| MSDS | / | Flash Point | 224.2±27.3 °C |
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Names
| Name | Propargyl-PEG8-alcohol |
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| Synonym | More Synonyms |
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Propargyl-PEG7-alcohol BiologicalActivity
| Description | Propargyl-PEG7-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
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| References | [1]. Goswami LN, et al. Efficient synthesis of diverse heterobifunctionalized clickable oligo(ethylene glycol) linkers: potential applications in bioconjugation and targeted drug delivery. Org Biomol Chem. 2013 Feb 21;11(7):1116-26. |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 447.2±40.0 °C at 760 mmHg |
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| Molecular Formula | C17H32O8 |
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| Molecular Weight | 364.431 |
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| Flash Point | 224.2±27.3 °C |
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| Exact Mass | 364.209717 |
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| LogP | -2.40 |
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| Vapour Pressure | 0.0±2.5 mmHg at 25°C |
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| Index of Refraction | 1.464 |
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| InChIKey | QIJKIPMHDKPKLA-UHFFFAOYSA-N |
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| SMILES | C#CCOCCOCCOCCOCCOCCOCCOCCO |
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| Storage condition | 2-8°C |
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Synonyms
| 3,6,9,12,15,18,21-Heptaoxatetracos-23-yn-1-ol |
| MFCD28950752 |
