Introduction：Basic information about CAS 1425973-14-3|NH2-PEG7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | NH2-PEG7 |
|---|
| CAS Number | 1425973-14-3 | Molecular Weight | 325.398 |
|---|
| Density | 1.1±0.1 g/cm3 | Boiling Point | 427.3±40.0 °C at 760 mmHg |
|---|
| Molecular Formula | C14H31NO7 | Melting Point | / |
|---|
| MSDS | / | Flash Point | 212.2±27.3 °C |
|---|
Names
| Name | Amino-PEG7-alcohol |
|---|
| Synonym | More Synonyms |
|---|
NH2-PEG7 BiologicalActivity
| Description | NH2-PEG7 is a PROTAC linker, which refers to the PEG composition. NH2-PEG7 can be used in the synthesis of the PROTAC PARP1 degrader iRucaparib-AP6[1]. |
|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
|---|
| Target | PEGs |
|---|
| References | [1]. Wang S, et al. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation. Nat Chem Biol. 2019 Dec;15(12):1223-1231. |
|---|
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|
| Boiling Point | 427.3±40.0 °C at 760 mmHg |
|---|
| Molecular Formula | C14H31NO7 |
|---|
| Molecular Weight | 325.398 |
|---|
| Flash Point | 212.2±27.3 °C |
|---|
| Exact Mass | 325.210052 |
|---|
| LogP | -3.16 |
|---|
| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
|---|
| Index of Refraction | 1.464 |
|---|
| InChIKey | DIJOLBMLEZIVNG-UHFFFAOYSA-N |
|---|
| SMILES | NCCOCCOCCOCCOCCOCCOCCO |
|---|
Safety Information
Synonyms
| MFCD28385479 |
| 20-Amino-3,6,9,12,15,18-hexaoxaicosan-1-ol |
| 3,6,9,12,15,18-Hexaoxaeicosan-1-ol, 20-amino- |
