Introduction:Basic information about CAS 1425973-16-5|Azido-PEG5-acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Azido-PEG5-acid |
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| CAS Number | 1425973-16-5 | Molecular Weight | 379.406 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C13H25N3O7 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Azido-PEG5-acid |
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| Synonym | More Synonyms |
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Azido-PEG5-acid BiologicalActivity
| Description | Azido-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as the conjugate CPT-APO (CPT: Camptothecin (HY-16560)). |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Antibody-drug Conjugate >>ADC LinkerResearch Areas >>Inflammation/Immunology |
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| Target | Non-cleavable |
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| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
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| References | [1]. Zolotarskaya OY, et al. Click synthesis of a polyamidoamine dendrimer-based camptothecin prodrug. RSC Adv. 2015;5(72):58600-58608. Epub 2015 Jun 29. |
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Chemical & Physical Properties
| Molecular Formula | C13H25N3O7 |
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| Molecular Weight | 379.406 |
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| Exact Mass | 379.195465 |
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| LogP | -1.78 |
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| InChIKey | DPJUPQILWDVIKK-UHFFFAOYSA-N |
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| SMILES | [N-]=[N+]=NCCOCCOCCOCCOCCOCCC(=O)O |
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| Storage condition | 2-8°C |
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Synonyms
| 1-Azido-3,6,9,12,15,18-hexaoxahenicosan-21-oic acid |
| 3,6,9,12,15,18-Hexaoxaheneicosan-21-oic acid, 1-azido- |
| MFCD22056306 |