CAS 1425973-16-5|Azido-PEG5-acid

Introduction:Basic information about CAS 1425973-16-5|Azido-PEG5-acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameAzido-PEG5-acid
CAS Number1425973-16-5Molecular Weight379.406
Density/Boiling Point/
Molecular FormulaC13H25N3O7Melting Point/
MSDS/Flash Point/

Names

NameAzido-PEG5-acid
SynonymMore Synonyms

Azido-PEG5-acid BiologicalActivity

DescriptionAzido-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as the conjugate CPT-APO (CPT: Camptothecin (HY-16560)).
Related CatalogResearch Areas >>CancerSignaling Pathways >>Antibody-drug Conjugate >>ADC LinkerResearch Areas >>Inflammation/Immunology
Target

Non-cleavable

In VitroADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Zolotarskaya OY, et al. Click synthesis of a polyamidoamine dendrimer-based camptothecin prodrug. RSC Adv. 2015;5(72):58600-58608. Epub 2015 Jun 29.

Chemical & Physical Properties

Molecular FormulaC13H25N3O7
Molecular Weight379.406
Exact Mass379.195465
LogP-1.78
InChIKeyDPJUPQILWDVIKK-UHFFFAOYSA-N
SMILES[N-]=[N+]=NCCOCCOCCOCCOCCOCCC(=O)O
Storage condition2-8°C

Synonyms

1-Azido-3,6,9,12,15,18-hexaoxahenicosan-21-oic acid
3,6,9,12,15,18-Hexaoxaheneicosan-21-oic acid, 1-azido-
MFCD22056306
CAS 1425973-14-3|NH2-PEG7
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