Introduction：Basic information about CAS 145927-73-7|MS-PEG4-THP, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | MS-PEG4-THP |
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| CAS Number | 145927-73-7 | Molecular Weight | 356.43 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C14H28O8S | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Mes-PEG5- THP |
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| Synonym | More Synonyms |
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MS-PEG4-THP BiologicalActivity
| Description | MS-PEG4-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Molecular Formula | C14H28O8S |
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| Molecular Weight | 356.43 |
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| InChIKey | IHVHEXYPQZJGKH-UHFFFAOYSA-N |
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| SMILES | CS(=O)(=O)OCCOCCOCCOCCOC1CCCCO1 |
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Synonyms
