CAS 1778219-81-0|m-PEG3-Boc

Introduction:Basic information about CAS 1778219-81-0|m-PEG3-Boc, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Namem-PEG3-Boc
CAS Number1778219-81-0Molecular Weight248.32
Density/Boiling Point/
Molecular FormulaC12H24O5Melting Point/
MSDS/Flash Point/

Names

Namem-PEG3-t-butyl ester

m-PEG3-Boc BiologicalActivity

Descriptionm-PEG3-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

Alkyl/ether

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Darren H. Wakefield, et al. Poly(vinyl ester) Polymers for In Vivo Nucleic Acid Delivery. US20130121954A1.

Chemical & Physical Properties

Molecular FormulaC12H24O5
Molecular Weight248.32
InChIKeyCTECCIYKQSINBP-UHFFFAOYSA-N
SMILESCOCCOCCOCCC(=O)OC(C)(C)C
Storage condition2-8°C
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