Introduction：Basic information about CAS 864232-34-8|Licochalcone E, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Licochalcone E |
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| CAS Number | 864232-34-8 | Molecular Weight | 338.4 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C21H22O4 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
Licochalcone E BiologicalActivity
| Description | Licochalcone E, a flavonoid compound isolated from Glycyrrhiza inflate, inhibits NF-κB and AP-1 transcriptional activity through the inhibition of AKT and MAPK activation[1]. |
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| Related Catalog | Signaling Pathways >>PI3K/Akt/mTOR >>AktSignaling Pathways >>MAPK/ERK Pathway >>p38 MAPKResearch Areas >>Inflammation/Immunology |
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| Target | AKT, MAPK, NF-κB[1]. |
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| References | [1]. Lee HN, et al. Mechanisms by which licochalcone e exhibits potent anti-inflammatory properties: studies with phorbol ester-treated mouse skin and lipopolysaccharide-stimulated murine macrophages. Int J Mol Sci. 2013 May 24;14(6):10926-43. |
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Chemical & Physical Properties
| Molecular Formula | C21H22O4 |
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| Molecular Weight | 338.4 |
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| InChIKey | SWPKMTGYQGHLJS-RNVIBTMRSA-N |
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| SMILES | C=C(C)C(C)c1cc(C=CC(=O)c2ccc(O)cc2)c(OC)cc1O |
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