Introduction：Basic information about CAS 864238-20-0|MMAF intermediate 2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | MMAF intermediate 2 |
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| CAS Number | 864238-20-0 | Molecular Weight | 384.898 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C19H29ClN2O4 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | L-Phenylalanine, N-[(2R,3R)-3-methoxy-2-methyl-1-oxo-3-(2S)-2-pyrrolidinylpropyl]-, methyl ester, monohydrochloride (9CI) |
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| Synonym | More Synonyms |
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MMAF intermediate 2 BiologicalActivity
| Description | MMAF intermediate 2 is an intermediate for the synthesis of MMAF (HY-15579). MMAF (Monomethylauristatin F) is a potent inhibitor of tubulin polymerization and the cytotoxic (ADC Cytotoxin) component of classic antibody drug conjugates (ADCs), such as Vorsetuzumab mafodotin and SGN-CD19A[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
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| References | [1]. |
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Chemical & Physical Properties
| Molecular Formula | C19H29ClN2O4 |
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| Molecular Weight | 384.898 |
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| Exact Mass | 384.181580 |
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| InChIKey | IKNWSNCMBMHJAU-WOLLCHHQSA-N |
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| SMILES | COC(=O)C(Cc1ccccc1)NC(=O)C(C)C(OC)C1CCCN1.Cl |
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Synonyms
| Methyl N-{(2R,3R)-3-methoxy-2-methyl-3-[(2S)-2-pyrrolidinyl]propanoyl}-L-phenylalaninate hydrochloride (1:1) |
| L-Phenylalanine, N-[(2R,3R)-3-methoxy-2-methyl-1-oxo-3-[(2S)-2-pyrrolidinyl]propyl]-, methyl ester, hydrochloride (1:1) |
