(-)-Gallocatechin gallate CAS 4233-96-9
Introduction：Basic information about (-)-Gallocatechin gallate CAS 4233-96-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
(-)-Gallocatechin gallate Basic information
| Product Name: | (-)-Gallocatechin gallate |
| Synonyms: | Gallocatechin gallat;(-)-gallocatecholgallate;(2s-trans)-henyl)-2h-1-benzopyran-3-yleste;Gallic acid, catechin gallate;Glicentin-related polypeptide;()-Gallocatechin gallate, >=99%;(2H)-benzopyran-3,5,7-triol 3-(3,4,5-trihydroxybenzoate);(2S,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1 |
| CAS: | 4233-96-9 |
| MF: | C22H18O11 |
| MW: | 458.37 |
| EINECS: | 636-979-1 |
| Product Categories: | chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Catechins & Tannins |
| Mol File: | 4233-96-9.mol |
(-)-Gallocatechin gallate Chemical Properties
| Melting point | >179oC (dec.) |
| Boiling point | 909.1±65.0 °C(Predicted) |
| density | 1.90±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 7.75±0.25(Predicted) |
| form | Solid |
| color | Off-White to Pale Brown |
| biological source | green tea |
| Major Application | metabolomics vitamins, nutraceuticals, and natural products |
| InChI | 1S/C22H18O11/c23-10-5-12(24)11-7-18(33-22(31)9-3-15(27)20(30)16(28)4-9)21(32-17(11)6-10)8-1-13(25)19(29)14(26)2-8/h1-6,18,21,23-30H,7H2/t18-,21+/m1/s1 |
| InChIKey | WMBWREPUVVBILR-NQIIRXRSSA-N |
| SMILES | Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@@H](Oc2c1)c4cc(O)c(O)c(O)c4 |
| LogP | 2.080 (est) |
| CAS DataBase Reference | 4233-96-9(CAS DataBase Reference) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-26/36 |
| WGK Germany | 3 |
| RTECS | DH9000000 |
| HS Code | 29329990 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
| Chemical Properties | White crystalline powder, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from tea. |
| Uses | (-)-Gallocatechin Gallate is a catechins found in green tea that has shown to suppress the activity of cytochrome P 450 1A1. |
| Definition | ChEBI: (-)-gallocatechin gallate is a gallate ester obtained by formal condensation of the carboxy group of gallic acid with the (3R)-hydroxy group of (-)-gallocatechin. A natural product found in found in green tea. It has a role as an EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor, a human xenobiotic metabolite, an antineoplastic agent and a plant metabolite. It is a gallate ester, a polyphenol and a catechin. It is functionally related to a (-)-gallocatechin and a gallic acid. It is an enantiomer of a (+)-gallocatechin gallate. |
| Biological Activity | Tea catechins like (-)-Gallocatechin gallate are known to have antiviral, antioxidative, antimutagenic and antiobesity activities. It exhibits human immunodeficiency virus-1 (HIV-1) integrase inhibitory activity by disturbing the interaction between the human immunodeficiency virus-1 (HIV-1) integrase and virus DNA. GCG also shows impeding effect on the release of vero toxins (VTs) by enterohemorrhagic Escherichia coli. It displays an inhibitory effect on cholesterol absorption and is reported to be more effective than tea catechins in lowering plasma cholesterol, thus preventing atherosclerosis. |
(-)-Gallocatechin gallate Preparation Products And Raw materials
