Introduction：Basic information about (23R,24S)-24,25-Epoxy-23-hydroxy-5α-tirucall-7-en-3-one CAS 115404-57-4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
(23R,24S)-24,25-Epoxy-23-hydroxy-5α-tirucall-7-en-3-one Basic information
| Product Name: | (23R,24S)-24,25-Epoxy-23-hydroxy-5α-tirucall-7-en-3-one |
| Synonyms: | (23R,24S)-24,25-Epoxy-23-hydroxy-5α-tirucall-7-en-3-one;Niloticin;Lanost-7-en-3-one,24,25-epoxy-23-hydroxy-, (13a,14b,17a,20S,23R,24S)-;Lanost-7-en-3-one, 24,25-epoxy-23-hydroxy-, (13α,14β,17α,20S,23R,24S)- |
| CAS: | 115404-57-4 |
| MF: | C30H48O3 |
| MW: | 456.71 |
| EINECS: | |
| Product Categories: | Triterpenoids |
| Mol File: | 115404-57-4.mol |
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(23R,24S)-24,25-Epoxy-23-hydroxy-5α-tirucall-7-en-3-one Chemical Properties
| Melting point | 149-151 °C |
| Boiling point | 538.5±45.0 °C(Predicted) |
| density | 1.07±0.1 g/cm3(Predicted) |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Cryst. |
| pka | 14.37±0.20(Predicted) |
| color | White to off-white |
Safety Information
(23R,24S)-24,25-Epoxy-23-hydroxy-5α-tirucall-7-en-3-one Usage And Synthesis
| Uses | Niloticin, tetracyclic triterpenoid compound, is a osteoclastogenesis inhibitor. Niloticin shows anti-viral, antioxidative, and mosquitocidal activities. Niloticin inhibits osteoclastogenesis by blocking RANKL-RANK interaction and suppressing the AKT, MAPK, and NF-κB signaling pathways[1]. |
| References | [1] Xu H, et al. Niloticin inhibits osteoclastogenesis by blocking RANKL-RANK interaction and suppressing the AKT, MAPK, and NF-κB signaling pathways. Biomed Pharmacother. 2022 May;149:112902. DOI:10.1016/j.biopha.2022.112902 |
(23R,24S)-24,25-Epoxy-23-hydroxy-5α-tirucall-7-en-3-one Preparation Products And Raw materials
