Introduction：Basic information about (2R,3R)-2-Amino-3-methylpentanoic acid CAS 319-78-8, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
(2R,3R)-2-Amino-3-methylpentanoic acid Basic information
| Product Name: | (2R,3R)-2-Amino-3-methylpentanoic acid |
| Synonyms: | (2R,3R)-2-Amino-3-methylvaleric acid;D-Ile-OH;D-Isoleucine≥ 98% (TLC);D-Ile;D(-)-ISOLEUCINE;D-ISOLEUCINE;H-D-ILE-OH;[-]-2-AMINO-3-METHYLPENTANOIC ACID |
| CAS: | 319-78-8 |
| MF: | C6H13NO2 |
| MW: | 131.17 |
| EINECS: | 206-269-2 |
| Product Categories: | Amino Acid Derivatives;Amino Acids and Derivatives;alpha-Amino Acids;Amino Acids;Biochemistry;Amino Acids;bc0001 |
| Mol File: | 319-78-8.mol |
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(2R,3R)-2-Amino-3-methylpentanoic acid Chemical Properties
| Melting point | 272-274 °C |
| alpha | -37 º (c=5, 1 N HCl 24 ºC) |
| Boiling point | 225.8±23.0 °C(Predicted) |
| density | 1.1720 (estimate) |
| refractive index | -40.5 ° (C=4, 6mol/L HCl) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Aqueous Acid (Slightly), Water (Slightly) |
| pka | 2.57±0.24(Predicted) |
| form | Solid |
| color | White to Off-White |
| Major Application | cell analysis |
| InChI | InChI=1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m1/s1 |
| InChIKey | AGPKZVBTJJNPAG-RFZPGFLSSA-N |
| SMILES | C(O)(=O)[C@@H]([C@H](C)CC)N |
| CAS DataBase Reference | 319-78-8(CAS DataBase Reference) |
| EPA Substance Registry System | D-Isoleucine (319-78-8) |
Safety Information
| Hazard Codes | Xn |
| Risk Statements | 40 |
| Safety Statements | 24/25-36-22 |
| WGK Germany | 3 |
| RTECS | NR4700000 |
| HS Code | 29224995 |
| Storage Class | 11 - Combustible Solids |
| Toxicity | rat,LD50,intraperitoneal,6822mg/kg (6822mg/kg),BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)LUNGS, THORAX, OR RESPIRATION: DYSPNEA,Archives of Biochemistry and Biophysics. Vol. 64, Pg. 319, 1956. |
(2R,3R)-2-Amino-3-methylpentanoic acid Usage And Synthesis
| Chemical Properties | white to very slightly yellow powder |
| Uses | May contain up to 10% allo-isomer. |
| Uses | D-Isoleucine is not biosynthesized in the human body and is therefore categorized as an essential amino acid that must be obtained through diet. It is also an important building block that is used in the formation of hemoglobin in humans. |
| Definition | ChEBI: The D-enantiomer of isoleucine. |
| Biological Activity | D-Isoleucine may be used to help characterize and differentiate various D-amino acid oxidases. D-Isoleucine may be used to differentiate the activities of D- and L-isoleucine in processes such as the induction of pigmentation in B16F0 melanoma cells. |
(2R,3R)-2-Amino-3-methylpentanoic acid Preparation Products And Raw materials
| Raw materials | Acetic anhydride-->L-Isoleucine |
| Preparation Products | L-Isoleucine-->Cyclo(Ile-Ala) |
