(3R)-8-hydroxy-3-methyl-isochroman-1-one CAS 480-33-1

Introduction：Basic information about (3R)-8-hydroxy-3-methyl-isochroman-1-one CAS 480-33-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

(3R)-8-hydroxy-3-methyl-isochroman-1-one Basic information

• Product Name: (3R)-8-hydroxy-3-methyl-isochroman-1-one
• Synonyms: (3R)-8-hydroxy-3-methyl-isochroman-1-one;(R)-3,4-Dihydro-3-methyl-8-hydroxyisocoumarin;(R)-3,4-Dihydro-8-hydroxy-3-methyl-1H-2-benzopyran-1-one;[R,(-)]-3,4-Dihydro-3α-methyl-8-hydroxyisocoumarin;(R)-(-)-Mellein, (S)-(+)-Mellein;(R)-()-Mellein;1H-2-Benzopyran-1-one, 3,4-dihydro-8-hydroxy-3-methyl-, (3R)-;(R)-(-)-Mellein / (R)-(-)-Ochracin
• CAS: 480-33-1
• MF: C10H10O3
• MW: 178.18
• EINECS: 200-258-5
• Mol File: 480-33-1.mol

(3R)-8-hydroxy-3-methyl-isochroman-1-one Chemical Properties

• Melting point: 58-58.5 °C
• Boiling point: 392.7±42.0 °C(Predicted)
• density: 1.252±0.06 g/cm3(Predicted)
• storage temp.: Store at -20°C
• solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
• form: A crystalline solid
• pka: 9.86±0.40(Predicted)
• color: White to off-white
• CAS DataBase Reference: 480-33-1

(3R)-8-hydroxy-3-methyl-isochroman-1-one Usage And Synthesis

Uses

(R)-(?)-Mellein is a dihydroisocoumarin compound produced by A. ochraceus Wilhelm. It has a variety of biological activities including antibacterial, antimalarial, antifungal, and anticancer effects. (R)-(?)-Mellein inhibits proliferation of human breast cancer (MCF-7 and MDA-MB-468) and melanoma (SK-MEL-28 and Malme-3M) cell lines with IC50 values greater than 200 μM.[Cayman Chemical]