Introduction：Basic information about (R)-Duloxetine CAS 116539-60-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
(R)-Duloxetine Basic information
| Product Name: | (R)-Duloxetine |
| Synonyms: | (r)-duloxetine;(r)-n-methyl-gama-(1-naphthalenyloxy)-2-thiophenepropanamine;R-DULOXETINE HCL;N-methyl-3-(1-naphthalenyloxy)-3-thiophen-2-yl-1-propanamine;Ariclaim;CYMBALTA; ARICLAIM;2-Thiophenepropanamine, N-methyl-γ-(1-naphthalenyloxy)-, (γR);"(R)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan |
| CAS: | 116539-60-7 |
| MF: | C18H19NOS |
| MW: | 297.41 |
| EINECS: | 1312995-182-4 |
| Product Categories: | Pharmaceutical intermediate |
| Mol File: | 116539-60-7.mol |
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(R)-Duloxetine Chemical Properties
| Boiling point | 466.2±40.0 °C(Predicted) |
| density | 1.158 |
| pka | 10.02±0.10(Predicted) |
Safety Information
(R)-Duloxetine Usage And Synthesis
| Uses | (R)-Duloxetine is a dual inhibitor of serotonin and norepinephrine reuptake, effective in the treatment of emotional and physical symptoms of depression |
| Definition | ChEBI: (R)-duloxetine is a duloxetine. It is an enantiomer of a (S)-duloxetine. |
| Application | Duloxetine (duloxetine) is a third-generation antidepressant launched in 2002, and its hydrochloride is clinically used under the trade name Cymbalta (Cymbalta). |
| Synthesis | (R)-Duloxetine was prepared from (S)-3-N,N-dimethylamino-1-(2-thienyl)-1-propanol 67. |
(R)-Duloxetine Preparation Products And Raw materials
| Preparation Products | (±)-Duloxetine |
