(S)-Oxiranemethanol CAS 60456-23-7

Introduction：Basic information about (S)-Oxiranemethanol CAS 60456-23-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

(S)-Oxiranemethanol Basic information

• Product Name: (S)-Oxiranemethanol
• Synonyms: (S)-(-)-GLYCIDOL ((S)-(-)-2,3-EPOXY-1-PROPANOL);[(2r)-oxiran-2-yl]methanol;(S)-(-)-GLYCIDOL, 97% (98% EE/GLC);S-Glycidoe;(R)-3-Hydroxy-1,2-epoxypropane;(S)-(-)-2,3-Epoxy-1-propanol, (S)-(-)-Oxirane-2-methanol;(S)-(-)-Glycidol, (98% ee), 97%;(2S)-(-)-3-Hydroxy-1,2-propenoxide 97%
• CAS: 60456-23-7
• MF: C3H6O2
• MW: 74.08
• Product Categories: Chiral Compound;CHIRAL COMPOUNDS;chiral;API intermediates
• Mol File: 60456-23-7.mol

(S)-Oxiranemethanol Chemical Properties

• Melting point: 72-73 °C
• alpha: -15 º (neat)
• Boiling point: 66-67 °C19 mm Hg(lit.)
• density: 1.116 g/mL at 20 °C(lit.)
• refractive index: n20/D 1.433(lit.)
• Fp: 178 °F
• storage temp.: -20°C
• solubility: Soluble in chloroform, DMSO and methanol.
• pka: 14.62±0.10(Predicted)
• form: Liquid
• color: Pale yellow
• Optical Rotation: [α]20/D 15°, neat
• BRN: 79783
• InChI: 1S/C3H6O2/c4-1-3-2-5-3/h3-4H,1-2H2/t3-/m0/s1
• InChIKey: CTKINSOISVBQLD-VKHMYHEASA-N
• SMILES: OC[C@H]1CO1
• CAS DataBase Reference: 60456-23-7(CAS DataBase Reference)
• NIST Chemistry Reference: Oxiranemethanol, (S)-(60456-23-7)

Safety Information

• Hazard Codes: T
• Risk Statements: 45-60-21/22-23-36/37/38-68-41-37/38
• Safety Statements: 53-45-36/37/39-26
• RIDADR: UN 2810 6.1/PG 2
• WGK Germany: 3
• RTECS: RR0508100
• F: 10-21
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 29109000
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
• Hazard Classifications: Acute Tox. 2 Inhalation Acute Tox. 4 Dermal Acute Tox. 4 Oral Carc. 1B Eye Irrit. 2 Muta. 2 Repr. 1B Skin Irrit. 2 STOT SE 3

(S)-Oxiranemethanol Usage And Synthesis

Chemical Properties

Colorless to light yellow liqui

Uses

Employed in the synthesis of chiral (E)-allylic alcohol side-chains for introduction into prostacyclin and prostaglandin frameworks by cross-metathesis.

Definition

ChEBI: (S)-glycidol is a glycidol. It is functionally related to a (S)-1,2-epoxypropane. It is an enantiomer of a (R)-glycidol.

General Description

Glycidol or 2,3-epoxy-1-propanol is a highly reactive epoxy derivative, which is generally used as a monomer in the preparation of many polymers like polyesters,?polycarbonates,?polyurethanes,?and polyamides. It is also used in the preparation of detergents, rubbers, perfumes, fabric dyes, varnishes, cosmetics, and paints.

Purification Methods

[S(-)-isomer, § also available on polymer support, has b 49-50o/7mm, 66-67o/19mm, [ ] D -1 5o(neat)], [R(+)-isomer has b 56 -5 6 . 5o/11mm, d 4 1.117, n D 1.429, [ ] D +15o (neat)]. Purify glycidol by fractional distillation.

(S)-Oxiranemethanol Preparation Products And Raw materials

• Preparation Products: 2-(AMINOMETHYL)CYCLOPROPANECARBOXYLIC ACID-->(2R)-(-)-Glycidyl tosylate-->(R)-(-)-Benzyl glycidyl ether-->(R)-Glycidyl butyrate-->(R)-(-)-Methyl glycidyl ether-->2-Chloro-3-(oxiran-2-ylmethoxy)pyridine-->1,2-Propanediol, 3-(methylamino)-, (2R)-