1,2,3-Triacetyl-5-deoxy-D-ribose CAS 62211-93-2

Introduction：Basic information about 1,2,3-Triacetyl-5-deoxy-D-ribose CAS 62211-93-2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

1,2,3-Triacetyl-5-deoxy-D-ribose Basic information

• Product Name: 1,2,3-Triacetyl-5-deoxy-D-ribose
• Synonyms: 1,2,3-Triacetyl-5-deoxy-D-ribose;1,2,3-Triacetoxy-5-Deoxy Ribose;1,2,3-Triacetoxy-5-Deoxy-Beta-D-Ribofuranose;1,2,3-Tri-O-acetyl-5-deoxy-b-D-ribofuranose;1,2,6-TRI-O-ACETYL-3,4-DI-O-BENZYL-ALPHA-D-MANNOPYRANOSE;5-Deoxy-b-D-ribofuranose;ACETYLFURANOSIDE;b-D-Ribofuranose, 5-deoxy-,1,2,3-triacetate
• CAS: 62211-93-2
• MF: C11H16O7
• MW: 260.24
• EINECS: 612-957-7
• Product Categories: Carbohydrates & Derivatives;Intermediates;Capecitabine intermediate;Antineoplastic drug, 5-FU analog;bc0001;62211-93-2
• Mol File: 62211-93-2.mol

1,2,3-Triacetyl-5-deoxy-D-ribose Chemical Properties

• Melting point: 63-64°C
• alpha: -19.0 to -23.0 deg(C=2, EtOH)
• Boiling point: 315°C
• density: 1.23
• vapor pressure: 0.005-0.01Pa at 20-25℃
• Fp: 136°C
• storage temp.: Sealed in dry,2-8°C
• solubility: Soluble in ethanol
• form: Powder
• color: Yellow to Brown
• Optical Rotation: Consistent with structure
• InChI: InChI=1/C11H16O7/c1-5-9(16-6(2)12)10(17-7(3)13)11(15-5)18-8(4)14/h5,9-11H,1-4H3/t5-,9-,10-,11+/s3
• InChIKey: NXEJETQVUQAKTO-QPGVQJSANA-N
• SMILES: O([C@H]1[C@@H](O[C@H](C)[C@H]1OC(=O)C)OC(=O)C)C(=O)C |&1:1,2,4,6,r|
• LogP: 0.377-0.43 at 25℃
• Surface tension: 39.28mN/m at 1.01g/L and 20℃
• CAS DataBase Reference: 62211-93-2(CAS DataBase Reference)

Safety Information

• Safety Statements: 24/25
• HS Code: 29400090

1,2,3-Triacetyl-5-deoxy-D-ribose Usage And Synthesis

Chemical Properties

White Solid

Uses

Intermediate in the preparation of Cepecitabine.

Synthesis

Preparation of triacetyl ribose α isomers. The specific method uses 5-deoxy-D-ribose as starting material, which is acetylated in the presence of acrylate acetate/ferric chloride to obtain a mixture of triacetyl ribose isomers, which is further purified to the triacetyl ribose α isomer pure product. The reaction raw material 5-deoxy-D-ribose is a known compound, and samples thereof can be obtained by the synthetic method of Patent WO2008/105593, in which samples were prepared by heating and hydrolyzing with sulfuric acid from methyl-5-deoxy-2,3-O-isopropylidene-β-D-riboside (V).