Introduction：Basic information about 1,2-Dimethyl-5-nitroimidazole CAS 551-92-8, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
1,2-Dimethyl-5-nitroimidazole Basic information
| Product Name: | 1,2-Dimethyl-5-nitroimidazole |
| Synonyms: | DIMETRIDAZOLE;1,2-dimethyl-5-nitro-1h-imidazole;1,2-DIMETHYL-5-NITROIMIDAZOLE;1,2-dimethy-5-nitroimidazole;1,2-dimethyl-5-nitro-1h-imidazol;1,2-dimethyl-5-nitro-imidazol;1H-Imidazole, 1,2-dimethyl-5-nitro-;1H-Imidazole,1,2-dimethyl-5-nitro- |
| CAS: | 551-92-8 |
| MF: | C5H7N3O2 |
| MW: | 141.13 |
| EINECS: | 209-001-2 |
| Product Categories: | Pharmaceutical intermediates;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;API;nitro-compound;EMTRYL;Broad spectrum peptides anaerobic bacteria and drug resistance;551-92-8 |
| Mol File: | 551-92-8.mol |
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1,2-Dimethyl-5-nitroimidazole Chemical Properties
| Melting point | 177-182°C |
| Boiling point | 258.15°C (rough estimate) |
| density | 1.3818 (rough estimate) |
| refractive index | 1.6190 (estimate) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | ethanol: soluble50mg/mL |
| form | Crystalline Powder |
| pka | 2.81±0.25(Predicted) |
| color | white to yellow with a green cast |
| Water Solubility | 9.69g/L(20 ºC) |
| Merck | 14,3265 |
| BRN | 130665 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| Major Application | forensics and toxicology
pharmaceutical (small molecule) |
| InChI | 1S/C5H7N3O2/c1-4-6-3-5(7(4)2)8(9)10/h3H,1-2H3 |
| InChIKey | IBXPYPUJPLLOIN-UHFFFAOYSA-N |
| SMILES | Cc1ncc(n1C)[N+]([O-])=O |
| CAS DataBase Reference | 551-92-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Dimetridazole(551-92-8) |
| EPA Substance Registry System | 1,2-Dimethyl-5-nitroimidazole (551-92-8) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-36/37-22 |
| WGK Germany | 3 |
| RTECS | NI5075000 |
| HS Code | 29332900 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
1,2-Dimethyl-5-nitroimidazole Usage And Synthesis
| Chemical Properties | solid |
| Uses | An antihistomonal agent. Antiprotozoal (Histomonas). |
| Definition | ChEBI: Dimetridazole is a C-nitro compound that is 5-nitroimidazole in which the hydrogens at positions 1 and 2 are replaced by methyl groups. An antiprotozoal drug, it has been banned by both the Government of Canada and the European Union as a livestock feed additive owing to suspicions of it being carcinogenic. It has a role as an antiprotozoal drug and an antiparasitic agent. It is a C-nitro compound and a member of imidazoles. |
1,2-Dimethyl-5-nitroimidazole Preparation Products And Raw materials
| Raw materials | Nitric acid-->Dimethyl sulfate-->Glyoxal-->2-Methylimidazole-->2-Methyl-5-nitroimidazole-->2-METHYL-2-IMIDAZOLINE-->2-METHYL-5-NITROIMIDAZOLE |
| Preparation Products | 1H-Imidazol-5-amine,1,2-dimethyl-(9CI) |
