Introduction：Basic information about 1,4-Diiodobenzene CAS 624-38-4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
1,4-Diiodobenzene Basic information
| Product Name: | 1,4-Diiodobenzene |
| Synonyms: | 1,4-DIIODOBENZENE;4-DIIODOBENZENE;P-DIIODOBENZENE;1,4-diiodbenzene;1,4-diiodo-benzen;Benzene, 1,4-iodo-;Benzene, p-diiodo-;Benzene,1,4-diiode- |
| CAS: | 624-38-4 |
| MF: | C6H4I2 |
| MW: | 329.9 |
| EINECS: | 210-842-2 |
| Product Categories: | Building Blocks;Chemical Synthesis;Iodine Compounds;Aryl;Halogenated Hydrocarbons;Organic Building Blocks;C6;Halogenated Hydrocarbons;bc0001 |
| Mol File: | 624-38-4.mol |
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1,4-Diiodobenzene Chemical Properties
| Melting point | 131-133 °C (lit.) |
| Boiling point | 285 °C (lit.) |
| density | 2.350 |
| Fp | 285°C |
| refractive index | 1.6212 |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | Crystalline Powder |
| color | White to beige |
| Water Solubility | Soluble in ether and ethanol. Insoluble in water. |
| Sensitive | Light Sensitive |
| BRN | 1904546 |
| Dielectric constant | 2.8799999999999999 |
| InChI | 1S/C6H4I2/c7-5-1-2-6(8)4-3-5/h1-4H |
| InChIKey | LFMWZTSOMGDDJU-UHFFFAOYSA-N |
| SMILES | Ic1ccc(I)cc1 |
| CAS DataBase Reference | 624-38-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzene, 1,4-diiodo-(624-38-4) |
| EPA Substance Registry System | Benzene, 1,4-diiodo- (624-38-4) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| F | 8 |
| TSCA | TSCA listed |
| HS Code | 29036990 |
| Storage Class | 11 - Combustible Solids |
1,4-Diiodobenzene Usage And Synthesis
| Chemical Properties | 1,4-Diiodobenzene appears as white to light orange crystals or powder. Its melting point is 131–132 °C, and it boils at 285 °C (sublimes). The compound is readily soluble in ether and ethanol, but insoluble in water. |
| Uses | 1,4-Diiodobenzene is used in Suzuki reaction. It is used as a precursor in the preparation of martinellic acid and 1,4-bis(p-R-phenylethynyl)benzenes. Further, it is employed in the preparation of 1,4-diiodo-2,5-didodecylbenzene , which is a starting reagent for the synthesis of oligo(1,4-phenylene ethynylene). It is also used in human and animal nutrition products including antiseptics and disinfectants. In addition to this, it used in polarizing films for liquid crystal display chemicals. |
| Preparation | 1,4-Diiodobenzene is obtained by diazotising p-iodoaniline followed by substitution. An alternative preparation method involves diazotising p-phenylenediamine hydrochloride, followed by substitution with potassium iodide. |
| Purification Methods | Crystallise it from EtOH or boiling MeOH, then dry it in air. [Beilstein 5 IV 700.] |
| References | [1] JENS CARDINALE Heinz H C Johannes Ermert. Convenient preparation of (4-iodophenyl)aryliodonium salts[J]. Tetrahedron, 2012, 68 22: Pages 4112-4116. DOI:10.1016/j.tet.2012.03.113.
[2] ROEL S. SÁNCHEZ-CARRERA. Charge-Transport Properties of the 1,4-Diiodobenzene Crystal: A Quantum-Mechanical Study[J]. Chemistry of Materials, 2008, 20 18: 5832-5838. DOI:10.1021/cm801108c.
[3] DU ZONG-DA Yang C X Cui Yuan Yuan. Synthesis of silica amino-functionalized microporous organic network composites for efficient on-line solid phase extraction of trace phenols from water.[J]. Journal of Chromatography A, 2020, 1616: 460791. DOI:10.1016/j.chroma.2019.460791. |
1,4-Diiodobenzene Preparation Products And Raw materials
| Raw materials | 4-Iodoaniline-->p-Phenylenediamine dihydrochloride-->Potassium iodide |
| Preparation Products | p-Terphenyl-->4-Iodobiphenyl-->1,4-Benzenedipropanal-->1,4-Bis(trifluoromethyl)-benzene-->N-PHENYLCARBAZOLE HYDROCHLORIDE-->1,2-Diiodobenzene-->1 4-BIS(DIPHENYLAMINO)BENZENE-->4,4'-Diiodobiphenyl-->P-DIVINYLBENZENE 85-->(9-(4-IODOPHENYL))-9H-CARBAZOLE |
