1-Bromo-2-chloroethane CAS 107-04-0

Introduction：Basic information about 1-Bromo-2-chloroethane CAS 107-04-0, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

1-Bromo-2-chloroethane Basic information

• Product Name: 1-Bromo-2-chloroethane
• Synonyms: 1-Brom-2-chlorethan;1-bromo-2-chloro-ethan;1-chloro-bromoethane(cbe);2-Bromo-1-chloroethane;1-Bromo-2-chloroethane, 98+%;ethylenbromchlorid;ai3-52297;beta-Chloroethyl bromide
• CAS: 107-04-0
• MF: C2H4BrCl
• MW: 143.41
• EINECS: 203-456-0
• Product Categories: omega-Haloalkyl Chlorides;omega-Functional Alkanols, Carboxylic Acids, Amines & Halides;Alkyl;Building Blocks;Chemical Synthesis;Halogenated Hydrocarbons;Organic Building Blocks;API Intermediate;bc0001
• Mol File: 107-04-0.mol

1-Bromo-2-chloroethane Chemical Properties

• Melting point: −18-−14 °C(lit.)
• Boiling point: 106-107 °C(lit.)
• density: 1.723 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.4884(lit.)
• Fp: 104-107°C
• storage temp.: Store below +30°C.
• solubility: water: soluble
• form: Liquid
• color: Clear colorless to slightly yellow
• Water Solubility: 7 g/L (20 ºC)
• Sensitive: Light Sensitive
• BRN: 605265
• Dielectric constant: 7.1399999999999997
• InChI: 1S/C2H4BrCl/c3-1-2-4/h1-2H2
• InChIKey: IBYHHJPAARCAIE-UHFFFAOYSA-N
• SMILES: ClCCBr
• CAS DataBase Reference: 107-04-0(CAS DataBase Reference)
• NIST Chemistry Reference: Ethane, 1-bromo-2-chloro-(107-04-0)
• EPA Substance Registry System: 1-Bromo-2-chloroethane (107-04-0)

Safety Information

• Hazard Codes: T
• Risk Statements: 45-20/21-25-37/38-68-36/37/38-23/25
• Safety Statements: 53-36/37-45-38-36/37/39-28A
• RIDADR: UN 2810 6.1/PG 2
• WGK Germany: 3
• RTECS: KH6500000
• TSCA: TSCA listed
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 29034980
• Storage Class: 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
• Hazard Classifications: Acute Tox. 3 Oral Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Carc. 1B Skin Irrit. 2 STOT SE 3
• Hazardous Substances Data: 107-04-0(Hazardous Substances Data)
• Toxicity: rat,LD50,oral,64mg/kg (64mg/kg),"Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 4, Pg. 73, 1969.

1-Bromo-2-chloroethane Usage And Synthesis

Chemical Properties

Clear colorless to slightly yellow liquid

Uses

1-Bromo-2-chloroethane was used in regio- and diastereoselective synthesis of 2-alkylidenetetrahydrofurans. 1-Bromo-2-chloroethane is used as a solvent and as an intermediate for organic synthesis. It is used as a as fumigant.

Definition

ChEBI: A bromoalkane that is bromoethane substituted by a chloro group at position 2.

General Description

Clear colorless liquid with a sweet chloroform-like odor.

Air & Water Reactions

Slightly water soluble.

Reactivity Profile

1-Bromo-2-chloroethane is incompatible with strong bases, strong oxidizing agents and magnesium .

Fire Hazard

Literature sources indicate that 1-Bromo-2-chloroethane is nonflammable.

Synthesis

Take chloroethanol as raw material, react with phosphorus tribromide under stirring, the reaction is carried out at 20~30??, after the completion of the reaction, it is washed with diluent and water successively, static layering, after separating out the aqueous layer, drying is carried out, and finally distillation under reduced pressure can be produced.

Purification Methods

Wash it with conc H2SO4, water, 10% Na2CO3 solution, and again with water, then dry with CaCl2 and fractionally distil before use. [Beilstein 1 H 89, 1 I 28, 1 II 61, 1 III 179, 1 IV 155.]

1-Bromo-2-chloroethane Preparation Products And Raw materials

• Raw materials: Sodium carbonate-->2-Chloroethanol-->1-CHLORO-2-IODOETHANE-->2,2'-Dibromodiethyl ether
• Preparation Products: 1-(2-CHLOROETHYL)NAPHTHALENE-->1,2-DIFLUOROETHANE-->4-(2-Chloroethyl)morpholine-->1-(2-Chloroethoxy)-4-nitrobenzene-->2-CHLOROETHYL PHENYL SULFIDE-->ETHYL 1-CYANOCYCLOPROPANECARBOXYLATE-->1-(5-broMopyridin-3-yl)cyclopropanecarbonitrile-->1-(3-METHOXYPHENYL)CYCLOPROPANECARBONITRILE-->N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid-->1-(2-CHLOROETHOXY)-4-FLUOROBENZENE(WXC08215)-->1H-Isoindole-1,3(2H)-dione, 2-(2-chloroethoxy)-