Introduction：Basic information about 2,2'-Cyclouridine CAS 3736-77-4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
2,2'-Cyclouridine Basic information
| Product Name: | 2,2'-Cyclouridine |
| Synonyms: | 2,2'-ANHYDRO-1(BETA-D-ARABINOFURANOSYL)URACIL;2, 2'-ANHYDRO-1-(B-D-ARABINOFURANOSYL) URACIL;2,2'-Cyclouridine;BETA-D-O(2),2'-CYCLOURIDINE;02,2-Cycloridine;[2R-(2alpha,3beta,3abeta,9abeta)]-2,3,3a,9a-tetrahydro-3-hydroxy-(hydroxymethyl)-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one;2,2'-Anhydro-1(-D-arabinofuranosyl)uracil;3736-77-4 2,2'-Anhydrouridine 7410 |
| CAS: | 3736-77-4 |
| MF: | C9H10N2O5 |
| MW: | 226.19 |
| EINECS: | 223-107-6 |
| Product Categories: | Building Blocks;C9 to C11;Chemical Synthesis;Heterocyclic Building Blocks;Heterocyclic Building Blocks;Pyrimidines;Building Blocks;Biochemistry;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Heterocyclic Compounds;3736-77-4 |
| Mol File: | 3736-77-4.mol |
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2,2'-Cyclouridine Chemical Properties
| Melting point | 248-251 °C(lit.) |
| alpha | -21°(19℃, c=4, H2O) |
| Boiling point | 456.3±55.0 °C(Predicted) |
| density | 2.01±0.1 g/cm3(Predicted) |
| refractive index | -20 ° (C=4, H2O) |
| storage temp. | -20°C |
| solubility | DMSO:2.0(Max Conc. mg/mL);8.84(Max Conc. mM)
PBS (pH:7.2):1.0(Max Conc. mg/mL);4.42(Max Conc. mM) |
| pka | 12.55±0.40(Predicted) |
| form | powder to crystal |
| color | White to Almost white |
| Optical Rotation | [α]19/D 21°, c = 4 in H2O |
| InChI | InChI=1S/C9H10N2O5/c12-3-4-6(14)7-8(15-4)11-2-1-5(13)10-9(11)16-7/h1-2,4,6-8,12,14H,3H2/t4-,6-,7+,8-/m1/s1 |
| InChIKey | UUGITDASWNOAGG-CCXZUQQUSA-N |
| SMILES | C12O[C@@]3([H])[C@H](O)[C@@H](CO)O[C@@]3([H])N1C=CC(=O)N=2 |
| CAS DataBase Reference | 3736-77-4 |
Safety Information
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| HS Code | 29349990 |
| Storage Class | 11 - Combustible Solids |
2,2'-Cyclouridine Usage And Synthesis
| Description | 2,2'-Cyclouridine is a research tool for anticancer and antiviral studies. This works by inhibiting uridine phosphorylase, a key enzyme targeted by some antitumor drugs. |
| Chemical Properties | White powder |
| Uses | O2,2''-Cyclouridine is a research tool for anticancer and antiviral studies. |
| Uses | Research tool for antiviral and anticancer studies.1 |
2,2'-Cyclouridine Preparation Products And Raw materials
| Raw materials | 1-beta-D-Arabinofuranosyluracil |
