Introduction：Basic information about 2,3-Dichlorophenol CAS 576-24-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
2,3-Dichlorophenol Basic information
| Product Name: | 2,3-Dichlorophenol |
| Synonyms: | 2,3-DICHLOROPHENOL;2,3-dichloro-pheno;2 3-DICHLOROPHENOL 1000MG NEAT;2,3-DICHLOR-PHENOL;2,3-Dichlorophenol,98+%;Phenol, 2,3-dichloro-;2,3-DICHLOROPHENOL 99+%;2,3-two chlorophenol |
| CAS: | 576-24-9 |
| MF: | C6H4Cl2O |
| MW: | 163 |
| EINECS: | 209-399-8 |
| Product Categories: | alcohol| alkyl chloride;Phenol&Thiophenol&Mercaptan;Chlorine Compounds;Phenols;Alphabetic;D;Organic Building Blocks;Oxygen Compounds;DIA - DIC;Building Blocks;C6 to C8;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Aromatic Phenols |
| Mol File: | 576-24-9.mol |
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2,3-Dichlorophenol Chemical Properties
| Melting point | 56 °C |
| Boiling point | 214 °C |
| density | 1.40 g/cm3 (25℃) |
| refractive index | 1.4430 (estimate) |
| Fp | 115 °C |
| storage temp. | 0-6°C |
| solubility | 3600mg/l (experimental) |
| form | powder |
| pka | 7.44(at 25℃) |
| color | White to Light red to Green |
| Water Solubility | <0.1 g/100 mL at 20 ºC |
| BRN | 2043615 |
| Stability: | Stable. Incompatible with oxidizing agents, acid chlorides, acid anhydrides. |
| InChI | 1S/C6H4Cl2O/c7-4-2-1-3-5(9)6(4)8/h1-3,9H |
| InChIKey | UMPSXRYVXUPCOS-UHFFFAOYSA-N |
| SMILES | Oc1cccc(Cl)c1Cl |
| CAS DataBase Reference | 576-24-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Phenol, 2,3-dichloro-(576-24-9) |
| EPA Substance Registry System | 2,3-Dichlorophenol (576-24-9) |
Safety Information
| Hazard Codes | Xn,Xi,N,C |
| Risk Statements | 22-36/38-51/53-34 |
| Safety Statements | 26-28-61-45-36/37/39 |
| RIDADR | UN 2020 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | SK8450000 |
| Hazard Note | Irritant |
| TSCA | TSCA listed |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29081000 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2 |
| Hazardous Substances Data | 576-24-9(Hazardous Substances Data) |
2,3-Dichlorophenol Usage And Synthesis
| Chemical Properties | 2,3-dichlorophenol appears as light brown crystalline solid. Soluble in ether, chloroform and hot ethanol, insoluble in water and benzene. |
| Uses | 2,3-Dichlorophenol is a chemical reagent used in the synthesis of a small molecule IL-2 inhibitor. |
| Preparation | 2,3-Dichlorophenol is obtained from 1,2,3-trichlorobenzene by sulfonation to salt and high pressure hydrolysis to 3,4-dichloro-2-hydroxybenzenesulfonic acid, then hydrolyzed by sulfuric acid to remove the sulfonic acid group. |
| General Description | Brown crystals (from ligroin, benzene). Taste threshold concentration 0.00004 mg/L. Odor threshold concentration 0.03 mg/L. |
| Air & Water Reactions | Insoluble in water. |
| Reactivity Profile | 2,3-Dichlorophenol is incompatible with acid chlorides, acid anhydrides and oxidizing agents. |
| Fire Hazard | Flash point data for 2,3-Dichlorophenol are not available. 2,3-Dichlorophenol is probably combustible. |
| Purification Methods | Crystallise it from ether. [Beilstein 6 IV 883.] |
2,3-Dichlorophenol Preparation Products And Raw materials
| Raw materials | 1,2,3-Trichlorobenzene-->o-hydroxybenzenesulphonic acid |
| Preparation Products | Ethacrynic acid-->Bithionol-->Ethyl(4-butyry-2,3-dichloro)phenoxyacetate-->4-Amino-2,3-dichlorphenol-->1-(2,3-DICHLORO-4-HYDROXYPHENYL)BUTAN-1-ONE-->2,6-Dichloroanisole-->FENHEXAMID-->1-Propanone, 1-(2,3-dichloro-4-hydroxyphenyl)--->3-(2,3-dichlorophenoxy)propanoic acid-->Acetic acid, [2,3-dichloro-4-(1-oxobutyl)phenoxy]-, ethyl ester |
