2',4'-Dihydroxy-3',6'-dimethoxychalcone CAS 129724-43-2

Introduction：Basic information about 2',4'-Dihydroxy-3',6'-dimethoxychalcone CAS 129724-43-2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

2',4'-Dihydroxy-3',6'-dimethoxychalcone Basic information

• Product Name: 2',4'-Dihydroxy-3',6'-dimethoxychalcone
• Synonyms: 1-(2,4-Dihydroxy-3,6-diMethoxyphenyl)-3-phenylprop-2-en-1-one;2',4'-DIHYDROXY-3',6'-DIMETHOXYC;2-Propen-1-one, 1-(2,4-dihydroxy-3,6-dimethoxyphenyl)-3-phenyl-, (2E)-;4'-Dihydroxy-3';6'-dimethoxychalcone;(2E)-1-(2,4-Dihydroxy-3,6-dimethoxyphenyl)-3-phenyl-2-propen-1-one
• CAS: 129724-43-2
• MF: C17H16O5
• MW: 300.31
• Mol File: 129724-43-2.mol

2',4'-Dihydroxy-3',6'-dimethoxychalcone Usage And Synthesis

Uses

2',4'-Dihydroxy-3',6'-dimethoxychalcone is a natural product that can be isolated from Polygonum Lapathifolium. 2',4'-Dihydroxy-3',6'-dimethoxychalcone inhibits the growth of CCRF-CEM leukaemia cells and CEM/ADR5000 cells, with IC50 values of 10.67 and 18.60 μM, respectively[1][2].

References

[1] Ahmed M, et al. Isoflavan-4-ol, dihydrochalcone and chalcone derivatives from Polygonum Lapathifolium. Phytochemistry, 1990, 29(6):2009-2011.
[2] Nkuété AH, et al. Anti-leukemia activity of semi-synthetic phenolic derivatives from Polygonum limbatum Meisn. Chem Cent J. 2015 Jun 24;9:40. DOI:10.1186/s13065-015-0115-2