2,5-Dichlorophenol CAS 583-78-8

Introduction：Basic information about 2,5-Dichlorophenol CAS 583-78-8, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

2,5-Dichlorophenol Basic information

• Product Name: 2,5-Dichlorophenol
• Synonyms: 2,5-dichloro-pheno;6-HYDROXY-1,4-DICHLOROBENZENE;2,5-DICHLORO-1-HYDROXY-BENZENE;2,5-DICHLOROPHENOL;2,5-DCP;DICHLOROPHENOL-2,5;Dichlorophenol,98%;2,5-DICHLOROPHENOL PESTANAL
• CAS: 583-78-8
• MF: C6H4Cl2O
• MW: 163
• EINECS: 209-520-4
• Product Categories: Aromatic Phenols;Organics;Phenol&Thiophenol&Mercaptan;Phenoles and thiophenoles;Chlorine Compounds;Phenols;Alpha sort;D;DAlphabetic;DIA - DIC;Pesticides&Metabolites;Organic Building Blocks;Oxygen Compounds;Volatiles/ Semivolatiles;K00001
• Mol File: 583-78-8.mol

2,5-Dichlorophenol Chemical Properties

• Melting point: 54-57 °C (lit.)
• Boiling point: 211 °C (lit.)
• density: 1.3446 (rough estimate)
• refractive index: 1.4430 (estimate)
• Fp: 100 °C
• storage temp.: 0-6°C
• solubility: 2000mg/l (experimental)
• pka: 7.53±0.10(Predicted)
• form: Crystals
• color: White to light brown
• Water Solubility: 3 g/L (20 ºC)
• BRN: 1907692
• InChI: 1S/C6H4Cl2O/c7-4-1-2-5(8)6(9)3-4/h1-3,9H
• InChIKey: RANCECPPZPIPNO-UHFFFAOYSA-N
• SMILES: Oc1cc(Cl)ccc1Cl
• LogP: 3.06 at 20℃
• CAS DataBase Reference: 583-78-8(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2,5-dichloro-(583-78-8)
• EPA Substance Registry System: 2,5-Dichlorophenol (583-78-8)

Safety Information

• Hazard Codes: C,N,Xn
• Risk Statements: 22-34-51/53-36/38
• Safety Statements: 26-36/37/39-45-61-37/39
• RIDADR: UN 2020 6.1/PG 3
• WGK Germany: 2
• RTECS: SK8600000
• TSCA: TSCA listed
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 29081000
• Storage Class: 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
• Hazard Classifications: Acute Tox. 4 Oral Aquatic Chronic 2 Eye Irrit. 2 Skin Irrit. 2
• Hazardous Substances Data: 583-78-8(Hazardous Substances Data)
• Toxicity: LD50 orally in Rabbit: 580 mg/kg

2,5-Dichlorophenol Usage And Synthesis

Chemical Properties

white to light brown crystals

Uses

2,5-Dichlorophenol is an intermediates in the manufacture of more complex chemical compounds such as fungicides.

Uses

2,5-Dichlorophenol may be used as an analytical reference standard for the determination of the analyte in water, and wood, paper, cardboard, fruits, and fruit juices using simultaneous dispersive liquid-liquid microextraction and derivatization followed by gas chromatography-electron-capture detection (GC-ECD) and gas chromatography-mass spectrometry (GC-MS), respectively.

Definition

ChEBI: A dichlorophenol with the chloro substituents at positions 2 and 5.

Synthesis Reference(s)

Journal of the American Chemical Society, 74, p. 3890, 1952 DOI: 10.1021/ja01135a052

General Description

Prisms (from benzene, petroleum ether) or white crystals. Odor threshold 30 μg/L at 68-72°F; 33 μg/L at 86°F. Taste threshold 0.5 μg/L.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2,5-Dichlorophenol is incompatible with acid chlorides, acid anhydrides and oxidizing agents.

Fire Hazard

Flash point data for 2,5-Dichlorophenol are not available. 2,5-Dichlorophenol is probably combustible.

Purification Methods

Crystallise it from ligroin and sublime it in a vacuum or distil it. [Beilstein 6 IV 942.]

2,5-Dichlorophenol Preparation Products And Raw materials

• Raw materials: Sodium nitrate-->2,4-Dichlorophenol-->2,5-Dichloroaniline-->NITROUS ACID-->Sodium 2,4,5-trichlorobenzenesulphonate-->Diphosphate-->3,4-DICHLOROANISOLE-->2,5-DICHLOROANISOLE-->2,4-DICHLOROANISOLE-->2-Bromo-1,4-dichlorobenzene-->3,4-Dichlorophenol-->3-Chlorophenol-->3,7-Dichlorodibenzofuran
• Preparation Products: Dicamba-->3,6-DICHLORO-2-HYDROXY BENZOIC ACID-->4-Bromo-2,5-dichlorophenol-->3,5-Dichlorophenol-->2,4,5-Trichlorophenoxyacetic acid-->2,3,4,6-TETRACHLOROPHENOL-->3,6-DICHLOROCATECHOL