2,5-Furandimethanol CAS 1883-75-6
Introduction：Basic information about 2,5-Furandimethanol CAS 1883-75-6, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
2,5-Furandimethanol Basic informationDescription Chemical Properties Preparation
| Product Name: | 2,5-Furandimethanol |
| Synonyms: | RARECHEM AL BD 0012;BIS (HYDROXYMETHYL)FURAN;5-(HYDROXYMETHYL)FURFURYL ALCOHOL;2,5-FURANDIMETHANOL;2,5-BIS(HYDROXYMETHYL)FURAN;2,5-dihydroxymethylfuran;furan-2,5-diyldimethanol;2,5-Bis(hydroxymethyl)furan,2,5-Furandimethanol |
| CAS: | 1883-75-6 |
| MF: | C6H8O3 |
| MW: | 128.13 |
| EINECS: | 217-544-1 |
| Product Categories: | Detergents;Mutagenesis Research Chemicals |
| Mol File: | 1883-75-6.mol |
2,5-Furandimethanol Chemical Properties
| Melting point | 74-77 °C |
| Boiling point | 275 °C |
| density | 1.283 |
| Fp | 120 °C |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Acetonitrile (Slightly), DMSO (Slightly) |
| form | Solid |
| pka | 13.74±0.10(Predicted) |
| color | Off-White to Light Yellow |
| InChI | InChI=1S/C6H8O3/c7-3-5-1-2-6(4-8)9-5/h1-2,7-8H,3-4H2 |
| InChIKey | DSLRVRBSNLHVBH-UHFFFAOYSA-N |
| SMILES | O1C(CO)=CC=C1CO |
| LogP | -1.326 (est) |
| EPA Substance Registry System | 2,5-Furandimethanol (1883-75-6) |
Safety Information
| Safety Statements | 24/25 |
| TSCA | TSCA listed |
| HS Code | 29321900 |
| Description | 2,5-Furandimethanol is white or internally white solid in appearance, soluble in water, ethanol, acetone, pyridine, tetrahydrofuran, but insoluble in ethane, toluene, and dichloroethane. |
| Chemical Properties | It has the properties of dihydric alcohol. It can be esterified, alkoxylated, glycidyl etherification, cyanoethylation, etherification, urea alkylation, resination, etc. |
| Preparation | 1. Preparation of adsorbent: Add 100Kg of ADS-17 medium polar adsorption resin, 5Kg of diethyl maleate, 0.5Kg of 2-methyl-4- (2,2,3-trimethyl-3-cyclopentene into the 2000L reactor -1-yl)-2-buten-1-ol, 700Kg water, 2Kg polyvinyl alcohol, 1Kg benzoyl peroxide, reacted at 80°C for 6h and then heated to 85°C for 2h, then heated to 95° C react for 6h, filter and dry to obtain adsorbent; 2 ·Adsorption purification of 2,5-furandimethanol: Mix 100Kg of technical grade 2,5-furandimethanol and 1000Kg of deionized water at 90°C for 3 hours, and then pass through a chromatography column equipped with adsorbent for adsorption at a temperature of 90°C and a flow rate of 3BV/h. After dehydration, a purified product of 2,5-furandimethanol can be obtained. |
| Description | 5-(Hydroxymethyl)furfuryl alcohol is a heterocyclic organic compound that is naturally produced by certain wood-inhabiting fungi. It can be derived by the reduction of the formyl group of 5-hydroxymethylfurfural. 5-(Hydroxymethyl)furfuryl alcohol can be used as a building block in the enzymatic synthesis of biobased polyesters. |
| Chemical Properties | Off-White to Pale Yellow Solid |
| Uses | 5-(Hydroxymethyl)furfuryl Alcohol is a secondary metabolite of Xylaramide, a new antifungal compound. |
| Definition | ChEBI: A furan carrying two hydroxymethyl substituents at the 2- and 5-positions. |
| Biological Activity | 5-(Hydroxymethyl)furfuryl alcohol is a heterocyclic organic compound that is naturally produced by certain wood-inhabiting fungi. It can be derived by the reduction of the formyl group of 5-hydroxymethylfurfural. 5-(Hydroxymethyl)furfuryl alcohol can be used as a building block in the enzymatic synthesis of biobased polyesters. |
| References | [1] G SCHNEIDER O S H Anke. Xylaramide, a new antifungal compound, and other secondary metabolites from Xylaria longipes.[J]. Zeitschrift Fur Naturforschung Section C-A Journal of Biosciences, 1996, 51 11-12: 802-806. DOI: 10.1515/znc-1996-11-1206 [2] Z L LIU. Adaptive response of yeasts to furfural and 5-hydroxymethylfurfural and new chemical evidence for HMF conversion to 2,5-bis-hydroxymethylfuran.[J]. Journal of Industrial Microbiology & Biotechnology, 2004, 31 8: 345-352. DOI: 10.1007/s10295-004-0148-3 [3] YAN ZHANG Thaddeus C E Bei Han. Biotransformation of furfural and 5-hydroxymethyl furfural (HMF) by Clostridium acetobutylicum ATCC 824 during butanol fermentation[J]. New biotechnology, 2012, 29 3: Pages 345-351. DOI: 10.1016/j.nbt.2011.09.001 [4] YI JIANG. Enzymatic Synthesis of Biobased Polyesters Using 2,5-Bis(hydroxymethyl)furan as the Building Block[J]. Biomacromolecules, 2014, 15 7: 2482-2493. DOI: 10.1021/bm500340w |
2,5-Furandimethanol Preparation Products And Raw materials
| Raw materials | Hydrochloric acid-->Ethyl acetate-->Methanol-->Dichloromethane-->Magnesium sulfate-->Sodium borohydride-->5-Hydroxymethylfurfural-->1-Hydroxyhexane-2,5-dione-->2,5-Hexanedione-->(5-METHYL-2-FURYL)METHANOL |
| Preparation Products | 8-oxa-3-azabicyclo[3.2.1]octane-->2,5-Dimethylfuran-->2-Methylfuran-->2,5-DIMETHYLTETRAHYDROFURAN-->5-Methyl furfural-->5,6-Dihydro-6-methyl-2H-pyran-3(4H)-one |
