Introduction：Basic information about 2,6-DI-O-METHYL-BETA-CYCLODEXTRIN CAS 51166-71-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
2,6-DI-O-METHYL-BETA-CYCLODEXTRIN Basic information
| Product Name: | 2,6-DI-O-METHYL-BETA-CYCLODEXTRIN |
| Synonyms: | DIMETHYL BETA-CYCLODEXTRIN;DIMEB;HEPTAKIS(2,6-DI-O-METHYL)-BETA-CYCLODEXTRIN;2,6-DI-O-METHYL-BETA-CYCLODEXTRIN;Dimethyl-beta-cyclodextrin, methylated beta-cyclodextrins;Di-O-methyl-β-cyclodextrin;Methyl-beta-cyclodextrin (2,6-Di-O-methyl- and partially 2,3,6-Tri-O-methyl- mixture);2,6-Dimethyl-b-cyclodextrin |
| CAS: | 51166-71-3 |
| MF: | C56H98O35 |
| MW: | 1331.36 |
| EINECS: | 1312995-182-4 |
| Product Categories: | Biochemistry;Cyclodextrins;Functional Materials;Macrocycles for Host-Guest Chemistry;Oligosaccharides;Sugars |
| Mol File: | 51166-71-3.mol |
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2,6-DI-O-METHYL-BETA-CYCLODEXTRIN Chemical Properties
| Melting point | 298-310 °C |
| Boiling point | 1203.6±65.0 °C(Predicted) |
| density | 1.40±0.1 g/cm3(Predicted) |
| refractive index | 163 ° (C=1, H2O) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | H2O: soluble |
| pka | 11.63±0.70(Predicted) |
| form | Crystalline Powder |
| color | White to faintly yellow |
| biological source | synthetic |
| Optical Rotation | [α]20/D +158±3°, c = 10% in H2O |
| Water Solubility | 212.6g/L(cold water) |
| BRN | 1679144 |
| InChIKey | QGKBSGBYSPTPKJ-UZMKXNTCSA-N |
| CAS DataBase Reference | 51166-71-3 |
Safety Information
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| RTECS | GU2293500 |
| HS Code | 29400090 |
| Storage Class | 11 - Combustible Solids |
2,6-DI-O-METHYL-BETA-CYCLODEXTRIN Usage And Synthesis
| Chemical Properties | White to faintly yellow crystalline powder |
| Uses | Induces the release of cholesterol from cholesterol-rich lipid rafts located on the surface of cells, making it a good agent for removing cholesterol from processed foods |
| Uses | Reactant involved in:
- Physicochemical studies of inclusion complexes
- Probing diffusion and single molecule interactions with reconstituted membrane proteins
- Interactions with micelles causing micellar rupture
- Studying cellular transport, used as a cell penetration enhancer
- Physicochemical and biopharmaceutical improvement of drugs particularly with solubilization and stability
- Interactions with cholesterol
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| General Description | Heptakis(2,6-di-O-methyl)-β-cyclodextrin is a hydrophilic derivative of cyclodextrin that possesses the ability to effectively dissolve lipophilic drugs like steroid hormones, vitamins A, E, and K, etc. It can be utilized to increase the dissolution and bioavailability of weakly water-soluble pharmaceutical compounds. |
2,6-DI-O-METHYL-BETA-CYCLODEXTRIN Preparation Products And Raw materials
| Raw materials | Pentobarbital sodium-->Naproxen sodium-->γ-Cyclodextrin-->Dimethyl sulfate-->Iodomethane-->β-Cyclodextrin-->Sodium salicylate |
| Preparation Products | Quinoline-N-oxide-->4-Nitropyridine N-oxide-->3-METHOXYPYRIDINE 1-OXIDE-->4-NITROQUINOLINE N-OXIDE-->Lidocaine |
