Introduction：Basic information about 2-Bromochlorobenzene CAS 694-80-4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
2-Bromochlorobenzene Basic information
| Product Name: | 2-Bromochlorobenzene |
| Synonyms: | O-CHLOROBROMOBENZENE;O-BROMOCHLOROBENZENE;1-bromo-2-chloro-benzen;1-Chloro-2-bromobenzene;2-Bromo-1-chlorobenzene;2-Chlorophenylbromide;Benzene, 1-bromo-2-chloro-;1-bromo-2-chlorobenzene solution |
| CAS: | 694-80-4 |
| MF: | C6H4BrCl |
| MW: | 191.45 |
| EINECS: | 211-775-1 |
| Product Categories: | Building Blocks;Chemical Synthesis;Chloro;Halogenated Hydrocarbons;Organic Building Blocks;alkyl chloride| alkyl bromide;Method 8020EPA;8000 Series Solidwaste Methods;A-BAlphabetic;Alpha Sort;B;Aryl;C6;Halogenated Hydrocarbons;Bromine Compounds;Chlorine Compounds;BI - BZChemical Class;BromoChemical Class;ChloroEPA;Halogenated;Method 8010EPA;Method 8021More...Close...;Volatiles/ Semivolatiles |
| Mol File: | 694-80-4.mol |
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2-Bromochlorobenzene Chemical Properties
| Melting point | -13--11°C |
| Boiling point | 204 °C(lit.) |
| density | 1.638 g/mL at 25 °C(lit.) |
| refractive index | n20/D 1.582(lit.) |
| Fp | 196 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | 0.045g/l |
| form | Liquid |
| color | Clear colorless to yellow-orange |
| Specific Gravity | 1.649 |
| Water Solubility | 0.045 G/L (25 ºC) |
| BRN | 1855303 |
| Dielectric constant | 6.7999999999999998 |
| InChI | 1S/C6H4BrCl/c7-5-3-1-2-4-6(5)8/h1-4H |
| InChIKey | QBELEDRHMPMKHP-UHFFFAOYSA-N |
| SMILES | Clc1ccccc1Br |
| CAS DataBase Reference | 694-80-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Chlorobromobenzene(694-80-4) |
| EPA Substance Registry System | Benzene, 1-bromo-2-chloro- (694-80-4) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38-39/23/24/25-23/24/25-20/22-11 |
| Safety Statements | 26-36-45-36/37-37/39-36/37/39-16-7 |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| TSCA | TSCA listed |
| HS Code | 29039990 |
| Storage Class | 10 - Combustible liquids |
| Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2 |
2-Bromochlorobenzene Usage And Synthesis
| Chemical Properties | clear colorless to yellow-orange liquid |
| Uses | 1-Bromo-2-chlorobenzene finds application in Gas Chromatography and Liquid Chromatography analysis. It is also used as an intermediate in pharmaceutical and synthetic chemistry. Further, it acts as a reagent in the preparation of arylpiperidines and aryltetrahydropyridines as 5-HT2C agonists. |
| Synthesis Reference(s) | Organic Syntheses, Coll. Vol. 3, p. 185, 1955
Tetrahedron Letters, 33, p. 3167, 1992 DOI: 10.1016/S0040-4039(00)79842-X |
2-Bromochlorobenzene Preparation Products And Raw materials
| Raw materials | Copper(I) chloride-->Cuprous bromide-->2-Chloroaniline |
| Preparation Products | 2-Dicyclohexylphosphino-2'-(N,N-dimethylamino)biphenyl-->X-PHOS-->2-Chlorophenylboronic acid-->Mitotan-->1-CHLORO-2-ETHYNYLBENZENE-->2,3,4,5-TETRAHYDRO-1H-BENZO[B][1,4]DIAZEPINE-->N-PHENYLCARBAZOLE HYDROCHLORIDE-->2',3,4-TRICHLOROBIPHENYL-->2,2'-DICHLOROBIPHENYL-->1-Octyl-2-methylindole-->ETHYL 2-(2-CHLOROPHENYL)ACETATE-->2-(2-chlorophenyl)cyclohexanone-->2-(Dicyclohexylphosphino)-2'-methoxybiphenyl-->1-(2-Chlorophenyl)piperazine-->2-CHLOROTHIOPHENOL |
