2-Chloro-5-methylpyridine CAS 18368-64-4

Introduction：Basic information about 2-Chloro-5-methylpyridine CAS 18368-64-4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

2-Chloro-5-methylpyridine Basic information

• Product Name: 2-Chloro-5-methylpyridine
• Synonyms: 2-chloro-5-methyl-pyridin;2-CHLORO-5-PICOLINE;2-CHLORO-5-METHYLPYRIDINE;2-CHLORO-5-PICOLINE 2-CHLORO-5-METHYLPYRIDINE;2-CHLORO-5-METHYLPYRIDINE (2-CHLORO-5-PICOLINE);6-CHLORO-3-METHYL PYRIDINE;6-CHLORO-3-PICOLINE;2-chloro-5-methylpyrdine
• CAS: 18368-64-4
• MF: C6H6ClN
• MW: 127.57
• EINECS: 418-050-0
• Product Categories: C6Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;pyridine series;Building Blocks;Heterocycle-Pyridine series;Pyridines;Chloropyridines;Halopyridines;C5 to C6;C6 to C7;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks;Pyridine;Boronic Acid
• Mol File: 18368-64-4.mol

2-Chloro-5-methylpyridine Chemical Properties

• Boiling point: 97 °C/30 mmHg (lit.)
• density: 1.169 g/mL at 25 °C (lit.)
• refractive index: n20/D 1.53(lit.)
• Fp: 195 °F
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• pka: 0.54±0.10(Predicted)
• form: Liquid
• color: Clear light yellow to straw-yellow or light pink-orange
• Specific Gravity: 1.169
• Water Solubility: Slightly soluble in water.
• InChI: InChI=1S/C6H6ClN/c1-5-2-3-6(7)8-4-5/h2-4H,1H3
• InChIKey: VXLYOURCUVQYLN-UHFFFAOYSA-N
• SMILES: C1(Cl)=NC=C(C)C=C1
• CAS DataBase Reference: 18368-64-4(CAS DataBase Reference)

Safety Information

• Hazard Codes: Xn,Xi
• Risk Statements: 21/22-38-52/53-36/37/38
• Safety Statements: 23-25-36/37-61-36-26
• WGK Germany: 2
• RTECS: US6740000
• HS Code: 29333999
• Storage Class: 10 - Combustible liquids
• Hazard Classifications: Acute Tox. 4 Dermal Acute Tox. 4 Oral Aquatic Chronic 3 Skin Irrit. 2
• Toxicity: rat,LD50,oral,1gm/kg (1000mg/kg),National Technical Information Service. Vol. OTS0545693,

2-Chloro-5-methylpyridine Usage And Synthesis

Chemical Properties

clear light yellow to straw-yellow liquid

Uses

2-Chloro-5-methylpyridine may be used in the synthesis of:

• 2-methylthio-5-pyridinemethylene amine
• 5-methyl-2,2′-bipyridine
• 1-(5′-methyl-2,2′-bipyridin-5-yl)-2,5-dimethyl-1H-pyrrole

General Description

2-Chloro-5-methylpyridine is a pesticide intermediate. Its synthesis by many methods has been reported.

2-Chloro-5-methylpyridine Preparation Products And Raw materials

• Raw materials: Hydrochloric acid-->Sodium nitrite-->Chlorobenzene-->Diisopropylamine-->Acetamide-->PROPYLENE-->2-Amino-5-methylpyridine-->2-Chloro-3-methylpyridine-->3-Picoline-N-oxide-->Nitrous acid methyl ester
• Preparation Products: Admire-->2-Chloronicotinic acid-->2-Chloro-5-trifluoromethylpyridine-->2-Chloro-5-(chloromethyl)pyridine-->2,3-Dichloro-5-(trifluoromethyl)pyridine-->6-BOC-HYDRAZINONICOTINIC ACID-->6-(METHYLTHIO)PYRIDINE-3-CARBOXYLIC ACID-->Acetamiprid-->2-MERCAPTO-5-METHYLPYRIDINE-->Pyridine, 5-(bromomethyl)-2-chloro- (9CI)-->2-Chloro-5-methylpyridine-3-carboxylic acid-->2-Pyridinecarboxylicacid,5-methyl-,methylester(9CI)-->2-chloro-5-methylpyridin-4-amine