Introduction：Basic information about 2-Chloronicotinyl chloride CAS 49609-84-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
2-Chloronicotinyl chloride Basic information
| Product Name: | 2-Chloronicotinyl chloride |
| Synonyms: | 2-CHLORONICOTINIC ACID CHLORIDE;2-CHLORONICOTINOYL CHLORIDE;2-CHLORONICOTINYL CHLORIDE;2-CHLOROPYRIDINE-3-CARBONYL CHLORIDE;2-Chloro-3-pyridine carboxylic acid chloride;2-Chloronictinoyl Chloride;2-Chloronicotinyl chloride, 98+%;3-Pyridinecarbonyl chloride, 2-chloro- (9CI) |
| CAS: | 49609-84-9 |
| MF: | C6H3Cl2NO |
| MW: | 176 |
| EINECS: | 610-464-1 |
| Product Categories: | pyridine series;Aromatics;Pyridines;Chloropyridines;Halopyridines;Heterocycles;ACIDHALIDE;Pyridine;C6Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;bc0001 |
| Mol File: | 49609-84-9.mol |
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2-Chloronicotinyl chloride Chemical Properties
| Melting point | 39-44 °C (lit.) |
| Boiling point | 96 °C |
| density | 1.2942 (rough estimate) |
| refractive index | 1.5680 (estimate) |
| Fp | >110°C |
| storage temp. | 0-10°C |
| solubility | Chloroform, DMSO, Ethyl Acetate |
| pka | -2.00±0.10(Predicted) |
| form | Low Melting Solid |
| color | White to beige-yellow |
| Sensitive | Moisture Sensitive |
| BRN | 119022 |
| InChI | InChI=1S/C6H3Cl2NO/c7-5-4(6(8)10)2-1-3-9-5/h1-3H |
| InChIKey | RXTRRIFWCJEMEL-UHFFFAOYSA-N |
| SMILES | C(Cl)(C1=CC=CN=C1Cl)=O |
| CAS DataBase Reference | 49609-84-9(CAS DataBase Reference) |
Safety Information
| Hazard Codes | C |
| Risk Statements | 14-29-34 |
| Safety Statements | 22-26-30-36/37/39-45-8-27 |
| RIDADR | 3096 |
| WGK Germany | 3 |
| Hazard Note | Corrosive/Moisture Sensitive |
| HazardClass | 8 |
| PackingGroup | II |
| HS Code | 29333990 |
| Storage Class | 8A - Combustible corrosive hazardous materials |
| Hazard Classifications | Skin Corr. 1B |
2-Chloronicotinyl chloride Usage And Synthesis
| Chemical Properties | 2-Chloronicotinyl chloride is off-white to brown solid |
| Uses | 2-Chloronicotinyl chloride is an intermediate of synergistic pesticide Boscalid. Also, used in the preparation of thieno[2.3-b]pyrrole derivatives as cannabinoid receptor agonists useful in mono- and combination therapy of disease s. |
| Uses | An intermediate of synergistic pesticide Boscalid. Also, used in the preparation of thieno[2.3-b]pyrrole derivatives as cannabinoid receptor agonists useful in mono- and combination therapy of diseases. |
2-Chloronicotinyl chloride Preparation Products And Raw materials
| Preparation Products | N-(2-Amino-4-methylpyridin-3-yl)-2-chloropyridine-3-carboxamide-->Nevirapine-->METHYL 2-CHLORONICOTINATE-->2-BROMO-3-(CHLOROMETHYL)PYRIDINE-->2-Chloronicotinamide-->4-[(2-CHLOROPYRIDIN-3-YL)CARBONYL]MORPHOLINE-->2-chloro-3-(pyrrolidin-1-ylcarbonyl)pyridine-->N-Butyl-2-chloronicotinamide-->CHEMBRDG-BB 5537391-->ethyl 3-(2-chloropyridin-3-yl)-3-oxopropanoate-->2-chloro-N-(4-methylphenyl)nicotinamide-->2-chloro-N-(1,3,4-thiadiazol-2-yl)pyridine-3-carboxamide-->(2-Chloropyridin-3-yl)bis(2-(methylthio)pyrimidin-4-yl)methanol |
