2-Dimethylaminoethyl chloride hydrochloride CAS 4584-46-7

Introduction：Basic information about 2-Dimethylaminoethyl chloride hydrochloride CAS 4584-46-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

2-Dimethylaminoethyl chloride hydrochloride Basic information

• Product Name: 2-Dimethylaminoethyl chloride hydrochloride
• Synonyms: N,N-Dimethylamino chloroethane hydrochloride;N,N-DIMETHYLAMINOETHYL CHLORIDE HYDROCHLORIDE;N,N-DIMETHYL-N-2-CHLOROETHYLAMMONIUM CHLORIDE;N-(2-CHLOROETHYL)-N,N-DIMETHYLAMMONIUM CHLORIDE;Chlorphenamine Impurity 5 HCl;2-chloro-n,n-dimethyl-ethanaminhydrochloride;2-chloro-n,n-dimethyl-ethylaminhydrochloride;N-(2-CHLOROETHYL)DIMETHYLAMINE HYDROCHLORIDE
• CAS: 4584-46-7
• MF: C4H11Cl2N
• MW: 144.04
• EINECS: 224-970-1
• Product Categories: Intermediates;Halogen compounds;For Chlorpheniramine's Production
• Mol File: 4584-46-7.mol

2-Dimethylaminoethyl chloride hydrochloride Chemical Properties

• Melting point: 201-204 °C(lit.)
• storage temp.: Store below +30°C.
• solubility: 2000g/l
• form: Crystalline Powder or Crystals
• color: White to brown-yellow
• Water Solubility: 2000 g/L (20 ºC)
• Sensitive: Hygroscopic
• BRN: 3591234
• Stability: Hygroscopic
• InChI: 1S/C4H10ClN.ClH/c1-6(2)4-3-5;/h3-4H2,1-2H3;1H
• InChIKey: LQLJZSJKRYTKTP-UHFFFAOYSA-N
• SMILES: [Cl-].ClCC[N+H](C)C
• CAS DataBase Reference: 4584-46-7(CAS DataBase Reference)
• EPA Substance Registry System: Ethanamine, 2-chloro-N,N-dimethyl-, hydrochloride (4584-46-7)

Safety Information

• Hazard Codes: T,N,T+
• Risk Statements: 22-24-36/37/38-68-51/53-26
• Safety Statements: 26-36/37-45-61-36/37/39-28A
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• RTECS: KQ9020000
• Autoignition Temperature: 220 °C
• TSCA: TSCA listed
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 29211980
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Acute Tox. 4 Oral Aquatic Chronic 2 Muta. 2 STOT RE 2
• Toxicity: LD50 orally in Rabbit: 238 mg/kg LD50 dermal Rabbit 290 mg/kg

2-Dimethylaminoethyl chloride hydrochloride Usage And Synthesis

Appearance

2-Dimethylaminoethyl chloride hydrochloride is white to Off-White Solid

Applications

2-Chloro-N,N-dimethylethylamine is a widely used as an intermediate and starting reagent for organic synthesis.

Dangerous Goods Info

Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Chemical Properties

Colorless to beige crystals

Uses

2-Chloro-N,N-dimethylethylamine hydrochloride (DMC) is used as intermediate for the synthesis of pharmaceuticals (e.g. bephenium hydroxnaphthoate, diltiazem, mepyramine and phenyltoloxamine). Product Data Sheet

Uses

2-Chloro-N,N-dimethylethylamine is a widely used as a intermediate and starting reagent for organic synthesis. Also acts as Intermediate for the syntheses of bephenium hydroxynaphthoate, diltiazem, mepyramine and phenyltoloxamine.

Definition

ChEBI: 2-dimethylaminoethyl chloride hydrochloride is a hydrochloride obtained by combining 2-dimethylaminoethyl chloride with one molar equivalent of hydrochloric acid. It is a hydrochloride and an organoammonium salt. It contains a 2-dimethylammonioethyl chloride.

Safety Profile

Poison by intraperitoneal and subcutaneous routes. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of Cland NOx

2-Dimethylaminoethyl chloride hydrochloride Preparation Products And Raw materials

• Raw materials: Thionyl chloride-->2-Dimethylaminoethanol-->Chloroacetic anhydride
• Preparation Products: 2-CHLORO-6-METHYLBENZALDEHYDE-->1-(2-DIMETHYLAMINOETHYL)PIPERAZINE-->4-[2-(DIMETHYLAMINO)ETHOXY]BENZALDEHYDE-->N'-BENZYL-N,N-DIMETHYLETHYLENEDIAMINE-->2-DIMETHYLAMINOETHANETHIOL HYDROCHLORIDE-->Bis[2-(dimethylamino)ethyl] persulfide-->Afimoxifene-->4-HYDROXYTAMOXIFEN-->Diltiazem-->dimethyl(2-phenoxyethyl)amine