Introduction：Basic information about 2-Methyl-2-thiazoline CAS 2346-00-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
2-Methyl-2-thiazoline Basic information
| Product Name: | 2-Methyl-2-thiazoline |
| Synonyms: | 2-methyl-2-thiazolidine;2-methyl-2-thiazolin;2-Methyl-4,5-dihydro-1,3-thiazole;2-Methyl-delta2-thiazoline;2-Methyldihydrothiazole;2-Thiazoline, 2-methyl-;METHYL-2-THIAZOLINE;2-METHYLTHIAZOLINE |
| CAS: | 2346-00-1 |
| MF: | C4H7NS |
| MW: | 101.17 |
| EINECS: | 219-071-6 |
| Product Categories: | Building Blocks;Heterocyclic Building Blocks;Thiazolines/Thiazolidines;Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;Alphabetical Listings;Flavors and Fragrances;M-N;thiazole Flavor;Heterocyclic Compounds |
| Mol File: | 2346-00-1.mol |
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2-Methyl-2-thiazoline Chemical Properties
| Melting point | -101.0 °C (lit.) |
| Boiling point | 144.0-145.0 °C (lit.) |
| density | 1.067 g/mL at 25 °C (lit.) |
| refractive index | n20/D 1.520(lit.) |
| Fp | 99 °F |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| form | liquid |
| pka | 5.26±0.10(Predicted) |
| color | colorless |
| Specific Gravity | 1.067 |
| Odor | at 0.10 % in propylene glycol. sulfurous musty meaty nutty |
| Odor Type | sulfurous |
| biological source | synthetic |
| BRN | 104274 |
| InChI | 1S/C4H7NS/c1-4-5-2-3-6-4/h2-3H2,1H3 |
| InChIKey | JUIQOABNSLTJSW-UHFFFAOYSA-N |
| SMILES | CC1=NCCS1 |
| LogP | 0.968 (est) |
| CAS DataBase Reference | 2346-00-1(CAS DataBase Reference) |
| NIST Chemistry Reference | Thiazole, 4,5-dihydro-2-methyl-(2346-00-1) |
| EPA Substance Registry System | Thiazole, 4,5-dihydro-2-methyl- (2346-00-1) |
Safety Information
| Risk Statements | 10 |
| Safety Statements | 16 |
| RIDADR | UN 1993 3/PG 3 |
| WGK Germany | 2 |
| RTECS | XJ4261470 |
| F | 8-10-23 |
| TSCA | TSCA listed |
| HazardClass | 3 |
| PackingGroup | III |
| HS Code | 29341000 |
| Storage Class | 3 - Flammable liquids |
| Hazard Classifications | Flam. Liq. 3 |
2-Methyl-2-thiazoline Usage And Synthesis
| Chemical Properties | colorless to orange-yellow liquid |
| Uses | Meyers reagent for aldehyde synthesis. |
| Uses | 2-Methyl-2-thiazoline is utilized in lithiation to generate an acetaldehyde enolate equivalent, facilitating the synthesis of mono-, di-, and trisubstituted acetaldehydes, β-hydroxy aldehydes, homoallylic alcohols, and α,α-disubstituted β-ethylenic methyl ketones. |
| Definition | ChEBI: 2-Methyl-4,5-dihydro-1,3-thiazole is a member of thiazoles. |
2-Methyl-2-thiazoline Preparation Products And Raw materials
| Raw materials | Toluene-->Triethylamine-->Acetyl chloride-->Monoethanolamine-->Phosphorus pentasulfide |
| Preparation Products | 2-METHYLTHIAZOLIDINE-->2-(2-Phenylethyl)thiazolidine, 97%-->3-ETHYL-2-METHYL-2-THIAZOLINIUM IODIDE, 98 |
